Train tickets from Boston, MA, US to Florence, SC, US
Next train departures
Next departures for Boston to Florence on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
South Station (Train Terminal)
Florence Station
Cheapest
Train
Boston Route 128, MA
Florence Station
Fastest
Train
South Station (Train Terminal)
Florence Station
No tags
Train
South Station (Train Terminal)
Florence Station
No tags
Train
South Station (Train Terminal)
Florence Station
No tags
Next departures for Boston to Florence on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
South Station (Train Terminal)
Florence Station
Cheapest
Train
Boston Route 128, MA
Florence Station
Fastest
Train
South Station (Train Terminal)
Florence Station
No tags
Train
South Station (Train Terminal)
Florence Station
No tags
Train
South Station (Train Terminal)
Florence Station
No tags
Last refresh of the prices: Last Wednesday at 7:54 PM EST.
Compare 2 ways to go from Boston to Florence
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 18 hours and with fares starting at just $121, it presents an excellent value for a comfortable ride.
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $121
Frequently asked questions about traveling from Boston, MA, US to Florence, SC, US by train
How much does a train ticket from Boston to Florence cost?
The average train ticket price from Boston to Florence is $328. The best way to find train tickets from Boston to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Boston to Florence?
A train trip between Boston and Florence is around 18h, although the fastest train will take about 17h 15m. This is the time it takes to travel the 729 miles that separates the two cities.
How many daily trains are there between Boston and Florence?
The number of trains from Boston to Florence can differ depending on the day of the week. On average, there are 10. Some trains are direct while others have layovers. Simplify your train trip from Boston to Florence by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Boston to Florence?
When taking the train from Boston to Florence, you can travel comfortably and safely with Amtrak.
What are the best sights and things to do in Florence?
Once in Florence, you can explore the city. The top sights and things to do are Basilica Santa Croce, Basilica di San Lorenzo, Museo degli Innocenti, Palazzo Vecchio, Leonardo Da Vinci Museum.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$275
11/20
$275
Today
$384
11/22
$420
11/23
$420
11/24
$382
11/25
$636
11/26
$575
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Nov 19, 2025 with a price of $275
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Florence, SC, US, as early as possible.
You can expect to pay from $275 to $1,573 for a train ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $382 which is on 2025-11-24.
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Nov 19, 2025 with a price of $275
