Train from Greenville, SC to Durham, NC, US: Tickets & Schedules

Next train departures

Next departures for Greenville to Durham on December 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Greenville Station
Durham StationCheapestFastest

Last refresh of the prices: Last Sunday at 9:15 PM EST.

Compare 2 ways to go from Greenville to Durham

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 4 hours 37 minutes and with fares starting at just $41, it presents an excellent value for a comfortable ride.

9bus per day
4h 37mAverage Duration
217 milesDistance
9kgCO₂ emissions
Average Price$41 - $174Average Duration4h 37m
9kg CO₂e
Average Price$67 - $719Average Duration8h
31kg CO₂e

Frequently asked questions about traveling from Greenville, SC to Durham, NC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Greenville to Durham?

    The cheapest train tickets from Greenville to Durham start from $67. The average price for this train route is around $78. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Greenville to Durham?

    The average train ride duration from Greenville to Durham is 8h, covering a distance of 213 miles (343 km). The quickest train can get you there in 7h and is operated by Amtrak.

  3. Which train operators service the Greenville to Durham route?

    Several major train operators operate on this route with 1 trains available per day.

  4. What is the earliest and latest departure time for the train from Greenville to Durham?

    The earliest train departs from Greenville to Durham at 2:23am. And the latest train departs at 2:23am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$71
11/27
$74
Today
$63
11/29
$87
11/30
$654
12/01
$490
12/02
$78
12/03
$71
busbud logoThe cheapest trip from Greenville, SC to Durham, NC, US was searched and found on Nov 28, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Durham, NC, US, as early as possible.

You can expect to pay from $63 to $693 for a train ticket from Greenville, SC to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-12-03.

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