Train tickets from Chicago to Spartanburg

Previously seen trips

Next departures for Chicago to Spartanburg on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Chicago (Union Station), IL
Spartanburg StationNo tags
AmtrakTrain
Chicago (Union Station), IL
Spartanburg StationNo tags
AmtrakTrain
Chicago (Union Station), IL
Spartanburg StationNo tags
AmtrakTrain
Chicago (Union Station), IL
Spartanburg StationNo tags
AmtrakTrain
Chicago (Union Station), IL
Spartanburg StationNo tags

Compare 2 ways to go from Chicago to Spartanburg

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Spartanburg. The journey takes about 1 day, 2 hours and with fares starting at just $110, it presents an excellent value for a comfortable ride.

9bus per day
1d 2hAverage Duration
564 milesDistance
23kgCO₂ emissions
Average Price$110 - $299Average Duration1d 2h
23kg CO₂e
Average Price$208 - $394Average Duration1d 8h
83kg CO₂e

Frequently asked questions about traveling from Chicago to Spartanburg by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/18
No data
11/19
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Today
$415
11/21
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11/22
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11/23
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11/24
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11/25
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busbud logoThe cheapest trip from Chicago to Spartanburg was searched and found on Nov 20, 2025 with a price of $415

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Spartanburg, as early as possible.

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