Bus Tickets from Wilmington, DE to Indianapolis

Previously seen trips

Next departures for Wilmington to Indianapolis on November 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Wilmington Bus Station
Downtown Transit CenterNo tags
GreyhoundBus
Wilmington Bus Station
Indianapolis Bus StationNo tags
GreyhoundBus
Wilmington Bus Station
Indianapolis Bus StationNo tags
Greyhound + FlixBus
Bus
Wilmington Bus Station
Downtown Transit CenterNo tags
GreyhoundBus
Wilmington Bus Station
Indianapolis Bus StationNo tags

Compare 2 ways to go from Wilmington to Indianapolis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Indianapolis. The journey takes about 20 hours 30 minutes and with fares starting at just $120, it presents an excellent value for a comfortable ride.

1train per day
20h 30mAverage Duration
563 milesDistance
82kgCO₂ emissions
Average Price$124 - $336Average Duration23h 45m
23kg CO₂e
Average Price$120 - $632Average Duration20h 30m
82kg CO₂e

Frequently asked questions about traveling from Wilmington, DE to Indianapolis by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/16
$153
11/17
$158
Today
No data
11/19
No data
11/20
No data
11/21
No data
11/22
No data
11/23
No data
busbud logoThe cheapest trip from Wilmington, DE to Indianapolis was searched and found on Nov 16, 2025 with a price of $153

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Indianapolis, as early as possible.

What's the cheapest way to go from Wilmington, DE to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

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