Next departures

Next departures for Syracuse to Rome on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Trenitalia Intercity
Syracuse
TerminiCheapestFastest
Trenitalia Intercity
Syracuse
TerminiNo tags
Flixbus
Terminal Interbus
Rome Tiburtina Bus StationNo tags
Trenitalia Intercity
Syracuse
TerminiNo tags
Flixbus
Terminal Interbus
Rome AnagninaNo tags

Last refresh of the prices: 11/12/2025 CET.

Compare 3 ways to go from Siracusa Train Station to Rome

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Rome. The journey takes about 19 hours 50 minutes and with fares starting at just $45, it presents an excellent value for a comfortable ride.

4bus per day
19h 50mAverage Duration
364 milesDistance
15kgCO₂ emissions
Average Price$45 - $178Average Duration19h 50m
15kg CO₂e
Average Price$66 - $267Average Duration11h 1m
14kg CO₂e
Carpool
Average Price$41 - $41Average Duration10h 40m
25kg CO₂e

Frequently asked questions about traveling from Syracuse to Rome by bus

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