Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Paysandu - ROU | No tags | ||||
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Estación Paysandú | No tags | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Estación Paysandú | No tags | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Paysandu - ROU | No tags | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Estación Paysandú | No tags |
Get from Santa Fe to Paysandú
The journey takes about 5 hours 25 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Fe and Paysandú?
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Stops in Paysandú
- ACerrito 1305, 60000 Paysandú, Departamento de Paysandú, Uruguay
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Frequently asked questions about traveling from Santa Fe, AR to Paysandú by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Fe to Paysandú?
The cheapest bus tickets from Santa Fe to Paysandú start from $68. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Fe to Paysandú?
The average bus trip duration from Santa Fe to Paysandú is 5h 25m, covering a distance of 161 miles (259 km). The quickest bus can get you there in 5h 10m and is operated by EGA.
Which bus companies service the Santa Fe to Paysandú route?
What is the earliest and latest departure time for the bus from Santa Fe to Paysandú?
The earliest bus departs from Santa Fe to Paysandú at 8:30pm. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Santa Fe to Paysandú?
A bus trip from Santa Fe to Paysandú generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santa Fe to Paysandú?
According to Busbud customers, the highest-rated bus company on this route is EGA, with an average rating of 4.5 out of 5 stars based on 596 reviews.
Which bus company has the best Wi-Fi from Santa Fe to Paysandú?
Based on reviews on Busbud, the bus company EGA has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Santa Fe to Paysandú?
According to Busbud traveller reviews, the most timely bus company on this route is EGA, with a punctuality rating of 4.5 out of 5 stars.
Which bus company has the cleanest buses from Santa Fe to Paysandú?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is EGA, with a cleanliness rating of 4.9 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe, AR to Paysandú was searched and found on Nov 28, 2025 with a price of $72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to Paysandú, as early as possible.
You can expect to pay from $72 to $90 for a bus ticket from Santa Fe, AR to Paysandú based on the last 2 days. You can expect to find the cheapest price for the trip at $72 which is on 2025-11-28.
