How much is the bus ticket from San Diego to Lafayette?

The cheapest bus tickets from San Diego to Lafayette start from $223. The average price for this route is around $288. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Diego to Lafayette?

The average bus trip duration from San Diego to Lafayette is 1d 22h, covering a distance of 1488 miles (2399 km). The quickest bus can get you there in 1d 15h and is operated by Greyhound .

Which bus companies service the San Diego to Lafayette route?

Several major bus companies operate on this route with 14 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from San Diego to Lafayette?

The earliest bus departs from San Diego to Lafayette at 6:45am. And the latest bus departs at 7:35pm.

What are the CO₂ emissions for the bus trip from San Diego to Lafayette?

A bus trip from San Diego to Lafayette generates an estimated 60 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from San Diego to Lafayette?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from San Diego to Lafayette?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from San Diego to Lafayette?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Diego to Lafayette?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus San Diego to Lafayette from $230 | Refundable Tickets

Previously seen trips

Next departures for San Diego to Lafayette on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	3:15pm	5716 Hardy Ave	2d	5:20pm	Lafayette Transit System	No tags
Greyhound + FlixBus	Bus	4:50pm	San Diego (Old Town-FlixBus)	1d 22h	5:20pm	Lafayette Transit System	No tags
Greyhound + FlixBus	Bus	4:50pm	San Diego (Old Town-FlixBus)	2d 6h	1:25am	TA Travel Center - Lafayette	No tags
FlixBus + Greyhound	Bus	5:10pm	UCSD Health La Jolla Station	1d 22h	5:20pm	Lafayette Transit System	No tags
Greyhound + FlixBus	Bus	5:10pm	UCSD Health La Jolla Station	2d 6h	1:25am	TA Travel Center - Lafayette	No tags

Compare 2 ways to go from San Diego to Lafayette

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Lafayette. The journey takes about 1 day, 22 hours 20 minutes and with fares starting at just $223, it presents an excellent value for a comfortable ride.

14bus per day

1d 22hAverage Duration

1488 milesDistance

60kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$223 - $404	Average Duration1d 22h	CO₂ emissions 60kg CO₂e
Train	Average Price$293 - $294	Average Duration1d 23h	CO₂ emissions 218kg CO₂e

Where are the popular stops in San Diego and Lafayette?

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Stops in Lafayette

A
TA Travel Center - Lafayette
1701 N University Ave, Lafayette, LA 70507, USA
Visit page
B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501
C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA

Compare bus companies

Greyhound

3.5/587,434 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,631 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from San Diego, CA, US to Lafayette, LA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Diego to Lafayette?
The cheapest bus tickets from San Diego to Lafayette start from $223. The average price for this route is around $288. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Diego to Lafayette?
The average bus trip duration from San Diego to Lafayette is 1d 22h, covering a distance of 1488 miles (2399 km). The quickest bus can get you there in 1d 15h and is operated by Greyhound.
Which bus companies service the San Diego to Lafayette route?
Several major bus companies operate on this route with 14 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from San Diego to Lafayette?
The earliest bus departs from San Diego to Lafayette at 6:45am. And the latest bus departs at 7:35pm.
What are the CO₂ emissions for the bus trip from San Diego to Lafayette?
A bus trip from San Diego to Lafayette generates an estimated 60 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Diego to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from San Diego to Lafayette?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Diego to Lafayette?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Diego to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/14

No data

12/15

No data

Today

$248

12/17

No data

12/18

$276

12/19

No data

12/20

$335

12/21

No data

The cheapest trip from San Diego, CA, US to Lafayette, LA was searched and found on Dec 16, 2025 with a price of $248

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Lafayette, LA, as early as possible.

You can expect to pay from $248 to $361 for a bus ticket from San Diego, CA, US to Lafayette, LA based on the last 2 days. You can expect to find the cheapest price for the trip at $276 which is on 2025-12-18.