How do I get from San Diego to Indianapolis without flying?

You have the option of traveling from one city to the other by either bus or train. Both are practical and sustainable ways to travel to Indianapolis. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long is the bus trip from San Diego to Indianapolis?

The average travel time from San Diego to Indianapolis is about 2d 9h, although the minimum time it takes to get there is 2d 1h with the fastest bus. This is the time it takes to travel the 1783 miles (2876 km) that separate the two cities.

How far is San Diego from Indianapolis?

About 1783 miles (2876 km) separate San Diego and Indianapolis.

What are the departure and arrival stations when taking the bus from San Diego to Indianapolis?

Most of the buses traveling from San Diego to Indianapolis leave from Mission Valley Sheraton and arrive at Greyhound Amtrak Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

How much does a bus ticket from San Diego to Indianapolis cost?

The average price of a one-way ticket from San Diego to Indianapolis is $203. In the last 30 days, the prices ranged from $115 to $408, so it's good to do your research before booking.

Can I take an overnight bus from San Diego to Indianapolis?

Yes, you can take a night bus to go from San Diego to Indianapolis. Make sure to pack a blanket and a snack to make your trip more comfortable.

San Diego (CA), US to Indianapolis Bus Tickets

Q: What is the cheapest way to go from San Diego to Indianapolis?

The cheapest way to travel this route is by bus. With prices starting at $115, you won't find a cheaper way to get there.

TodayMay 21

from $271

TomorrowMay 22

FriMay 23

SatMay 24

SunMay 25

MonMay 26

TueMay 27

WedMay 28

Cheap buses leaving today

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: May 21 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 24 at 8:25am
Destination city: Indianapolis
Destination location: Downtown Transit Center
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 2d 9h
This trip is recommended because it is: Fastest
Departure time: May 21 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 24 at 4:50am
Destination city: Indianapolis
Destination location: Indianapolis Bus Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 2d 6h
Departure time: May 21 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 24 at 4:50am
Destination city: Indianapolis
Destination location: Indianapolis Bus Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 2d 6h
Departure time: May 21 at 7:35pm
Departure city: San Diego
Departure location: Greyhound Bus Stop
Arrival time: May 24 at 2:20pm
Destination city: Indianapolis
Destination location: Indianapolis Northeast
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 2d 15h

Accepted payments

Compare 2 ways to go from San Diego to Indianapolis.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$115 - $408	Average Duration2d 9h	CO₂ emissions 72kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$208 - $542	Average Duration2d 9h	CO₂ emissions 261kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the bus from San Diego to Indianapolis

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 2 days, 9 hours 50 minutes and with fares starting at just $115, it presents an excellent value for a comfortable ride.

17bus per day

2d 9hAverage Duration

$115Cheapest ticket

72kgCO₂ emissions

Bus San Diego to Indianapolis: Trip Overview

Average ticket price$203

Average bus trip duration2d 9h

Number of daily buses17

Earliest bus departure7:15am

Distance1782 miles (2874 km)

Latest bus departure7:35pm

Compare bus companies

Greyhound

3.5/586,993 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/58,700 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Los Limousines, Tornado Bus, Valley Transit, Tufesa, Wanda Coach

San Diego to Indianapolis Bus

Busbud helps you find a bus from San Diego to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from San Diego to Indianapolis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Diego to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in San Diego and Indianapolis?

Stops in San Diego

A - Mission Valley Sheraton

B - Old Town Courtyard Marriot

C - Downtown Holiday Inn

D - Greyhound Station

E - Market St. & Park Blvd

F - San Ysidro McDonald's

Stops in Indianapolis

A - Greyhound Amtrak Station

Frequently asked questions for your trip San Diego (CA), US - Indianapolis

How do I get from San Diego to Indianapolis without flying?
How long is the bus trip from San Diego to Indianapolis?
How far is San Diego from Indianapolis?
What are the departure and arrival stations when taking the bus from San Diego to Indianapolis?
What is the cheapest way to go from San Diego to Indianapolis?
How much does a bus ticket from San Diego to Indianapolis cost?
Can I take an overnight bus from San Diego to Indianapolis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/19

$355

05/20

No data

Today

$215

05/22

No data

05/23

$150

05/24

$236

05/25

$307

05/26

$165

The cheapest trip from San Diego to Indianapolis was searched and found on May 23, 2025 with a price of $150

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Indianapolis, as early as possible.

You can expect to pay from $150 to $409 for a bus ticket from San Diego to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $150 which is on 2025-05-23.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Indianapolis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Indianapolis that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Indianapolis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from San Diego to Indianapolis?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time2d 9h	Avg Price$203	Daily Departures17
Vehicle TypeTrain	Travel Time2d 9h	Avg Price$327	Daily Departures6

Will you be returning to San Diego by bus?

Bus from San Diego to Indianapolis

You can also go to Indianapolis by train

Train from San Diego to Indianapolis

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from San Diego (CA), US to Indianapolis