Bus Tickets from Rochester, NY, US to San Diego, CA, US

Previously seen trips

Next departures for Rochester to San Diego on October 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Rochester
San Diego (Old Town-FlixBus)No tags
Greyhound + FlixBus
Rochester
UCSD Health La Jolla StationNo tags
Greyhound
Rochester
Greyhound Bus StopNo tags
FlixBus + Greyhound
Rochester
Downtown SD (Seaport)No tags
FlixBus + Greyhound
Rochester
Balboa ParkNo tags

Accepted payments

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Compare 2 ways to go from Rochester to San Diego

Bus
Average Price$239 - $475Average Duration3d 2h
91kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$434 - $548Average Duration2d 16h
329kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Rochester to San Diego

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 2 days, 16 hours 24 minutes and with fares starting at just $434, it presents an excellent value for a comfortable ride.

2train per day
2d 16hAverage Duration
$434Cheapest ticket
329kgCO₂ emissions

Bus Rochester, NY, US to San Diego, CA, US: Trip Overview

Average ticket price$354
Average bus trip duration3d 2h
Number of daily buses5
Earliest bus departure1:20am
Distance2246 miles (3621 km)
Latest bus departure11:50pm

Rochester to San Diego Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rochester to San Diego.

We make sure you can find a bus service from Rochester to San Diego from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Rochester, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Rochester, NY, US - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/20
$347
10/21
No data
Today
No data
10/23
No data
10/24
No data
10/25
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10/26
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10/27
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busbud logoThe cheapest trip from Rochester, NY, US to San Diego, CA, US was searched and found on Oct 20, 2025 with a price of $347

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to San Diego, CA, US, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rochester to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rochester to San Diego, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Rochester to San Diego.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rochester to San Diego.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Rochester, NY, US to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester, NY, US by bus?

Bus from San Diego, CA, US to Rochester, NY, US

You can also go to San Diego, CA, US by train

Train from Rochester, NY, US to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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