Next departures for Prague to Heidelberg on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Prague (Central Bus Station Florenc)
Alte Eppelheimer Straße
Cheapest
Bus
Prague (Na Knížecí)
Alte Eppelheimer Straße
Fastest
Bus
Prague (Central Bus Station Florenc)
Alte Eppelheimer Straße
No tags
Bus
Prague (Na Knížecí)
Alte Eppelheimer Straße
No tags
Bus
PRG Airport
Alte Eppelheimer Straße
No tags
Last refresh of the prices: Today at 10:11 AM CET.
Compare 3 ways to go from Prague to Heidelberg
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Heidelberg. The journey takes about 4 hours 50 minutes and with fares starting at just $26, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11165 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $26
Frequently asked questions about traveling from Prague to Heidelberg by bus
What is the travel distance from Prague to Heidelberg?
About 260 miles (419 km) separate Prague and Heidelberg.
What are the departure and arrival stations when taking the bus from Prague to Heidelberg?
The majority of buses traveling from Prague to Heidelberg start their journey at Florenc and wind up at Südseite am Willi-Brandt-Platz. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Heidelberg?
Once in Heidelberg, you can start exploring the city and discover its surroundings. The top sights and things to do are Solarboat Neckarsonne, Parks and Gardens, Segway-Tour, Walking Tour of the Old Town and Viewpoints.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
No data
11/26
$39
Today
No data
11/28
$44
11/29
$35
11/30
$24
12/01
No data
12/02
No data
The cheapest trip from Prague to Heidelberg was searched and found on Nov 30, 2025 with a price of $24
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Heidelberg, as early as possible.
You can expect to pay from $24 to $68 for a bus ticket from Prague to Heidelberg based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-11-30.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.