Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | City of Portland | Rochester | CheapestFastest |
Last refresh of the prices: Last Tuesday at 3:53 AM EST.
Get from Portland to Rochester
The journey takes about 16 hours 15 minutes and with fares starting at just $90, it presents an excellent value for a comfortable ride.
Where are the popular stops in Portland and Rochester?
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
Stops in Rochester
- A186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605
- BRush Rhees Library, 755 Library Road, Rochester, NY 14627
- C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Portland, ME to Rochester, NY, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Portland to Rochester?
The cheapest bus tickets from Portland to Rochester start from $90. The average price for this route is around $118. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Portland to Rochester?
The average bus trip duration from Portland to Rochester is 16h 15m, covering a distance of 369 miles (595 km). The quickest bus can get you there in 16h 15m and is operated by Greyhound.
Which bus companies service the Portland to Rochester route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Portland to Rochester?
The earliest bus departs from Portland to Rochester at 1:45pm. And the latest bus departs at 1:45pm.
What are the CO₂ emissions for the bus trip from Portland to Rochester?
A bus trip from Portland to Rochester generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, ME to Rochester, NY, US was searched and found on Jan 24, 2026 with a price of $140To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, ME to Rochester, NY, US, as early as possible.
You can expect to pay from $140 to $154 for a bus ticket from Portland, ME to Rochester, NY, US based on the last 2 days. You can expect to find the cheapest price for the trip at $140 which is on 2026-01-24.
