- Portland to Florence buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | City of Portland | Florence, SC | No tags | ||||
![]() | Bus | City of Portland | Bus station | No tags | ||||
FlixBus + Greyhound | Bus | City of Portland | Florence, SC | No tags |
Compare 2 ways to go from Portland to Florence
Among the sustainable travel choices, the Bus stands out as the good way to reach Florence. The journey takes about 22 hours and with fares starting at just $122, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$122 - $179 | Average Duration22h | 33kg CO₂e | ||
Train | Average Price$268 - $268 | Average Duration21h 52m | 121kg CO₂e |
Where are the popular stops in Portland and Florence?
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Portland, ME to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Portland to Florence?
The cheapest bus tickets from Portland to Florence start from $122. The average price for this route is around $122. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Portland to Florence?
The average bus trip duration from Portland to Florence is 22h, covering a distance of 827 miles (1333 km). The quickest bus can get you there in 22h and is operated by Greyhound.
Which bus companies service the Portland to Florence route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Portland to Florence?
The earliest bus departs from Portland to Florence at 1:45pm. And the latest bus departs at 1:45pm.
What are the CO₂ emissions for the bus trip from Portland to Florence?
A bus trip from Portland to Florence generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






