Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pittsburgh Intermodal Station | WJW Investments Bus Stop | Cheapest | ||||
| Bus | Pittsburgh Intermodal Station | WJW Investments Bus Stop | Fastest |
Last refresh of the prices: Today at 5:10 AM EST.
Get from Pittsburgh to Lexington
The journey takes about 12 hours 50 minutes and with fares starting at just $82, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and Lexington?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in Lexington
- A477 W New Circle Rd, Lexington, KY 40511
- B1801 Alexandria Dr, Lexington, KY 40504, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Pittsburgh to Lexington, KY by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pittsburgh to Lexington?
The cheapest bus tickets from Pittsburgh to Lexington start from $82. The average price for this route is around $127. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pittsburgh to Lexington?
The average bus trip duration from Pittsburgh to Lexington is 12h 50m, covering a distance of 290 miles (468 km). The quickest bus can get you there in 12h 50m and is operated by Greyhound.
Which bus companies service the Pittsburgh to Lexington route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Pittsburgh to Lexington?
The earliest bus departs from Pittsburgh to Lexington at 1:35am. And the latest bus departs at 10:50am.
What are the CO₂ emissions for the bus trip from Pittsburgh to Lexington?
A bus trip from Pittsburgh to Lexington generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Lexington, KY was searched and found on Nov 27, 2025 with a price of $92To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Lexington, KY, as early as possible.
You can expect to pay from $92 to $191 for a bus ticket from Pittsburgh to Lexington, KY based on the last 2 days. You can expect to find the cheapest price for the trip at $104 which is on 2025-12-01.
Top traveled bus routes
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