Next departures for Philadelphia to Indianapolis on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Philadelphia, 199 Spring Garden St
Downtown Transit Center
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Cherry Hill Mall
Indianapolis Bus Station
No tags
Next departures for Philadelphia to Indianapolis on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Indianapolis Bus Station
Cheapest
Bus
199 Spring Garden St.
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Downtown Transit Center
No tags
Bus
Philadelphia, 199 Spring Garden St
Downtown Transit Center
No tags
Next departures for Philadelphia to Indianapolis on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Indianapolis Bus Station
Cheapest
Bus
199 Spring Garden St.
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Downtown Transit Center
No tags
Bus
Philadelphia, 199 Spring Garden St
Downtown Transit Center
No tags
Next departures for Philadelphia to Indianapolis on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Indianapolis Bus Station
Cheapest
Bus
199 Spring Garden St.
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Downtown Transit Center
No tags
Bus
Cherry Hill Mall
Downtown Transit Center
No tags
Next departures for Philadelphia to Indianapolis on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Indianapolis Bus Station
Cheapest
Bus
199 Spring Garden St.
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Downtown Transit Center
No tags
Bus
Philadelphia, 199 Spring Garden St
Downtown Transit Center
No tags
Next departures for Philadelphia to Indianapolis on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
199 Spring Garden St.
Indianapolis Bus Station
Cheapest
Bus
199 Spring Garden St.
Indianapolis Bus Station
Fastest
Bus
199 Spring Garden St.
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Downtown Transit Center
No tags
Bus
Philadelphia, 199 Spring Garden St
Downtown Transit Center
No tags
Last refresh of the prices: Yesterday at 7:19 PM EST.
Compare 2 ways to go from Philadelphia to Indianapolis
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Indianapolis. The journey takes about 21 hours and with fares starting at just $101, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Philadelphia Indianapolis recent customer reviews
The bus was very late and the layover was two hours longer than they told us it would be.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Philadelphia, PA to Indianapolis by bus
What is the distance between Philadelphia and Indianapolis?
Philadelphia and Indianapolis are 583 miles (940 km) apart.
What are the departure and arrival stations when taking the bus from Philadelphia to Indianapolis?
If you're headed to Indianapolis from Philadelphia, chances are that your bus will depart from Philadelphia Airport and arrive at Greyhound Amtrak Station. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$106
11/20
$123
Today
$123
11/22
$120
11/23
$120
11/24
No data
11/25
$127
11/26
$135
The cheapest trip from Philadelphia, PA to Indianapolis was searched and found on Nov 19, 2025 with a price of $106
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Indianapolis, as early as possible.
You can expect to pay from $106 to $311 for a bus ticket from Philadelphia, PA to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-11-22.
The cheapest trip from Philadelphia, PA to Indianapolis was searched and found on Nov 19, 2025 with a price of $106
