Next departures for Mulhouse to Lyon on November 19
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Mulhouse
Perrache
CheapestFastest
Bus
Mulhouse
Perrache
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Next departures for Mulhouse to Lyon on November 21
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Gare routière de Mulhouse
Lyon - Perrache Bus Station
CheapestFastest
Next departures for Mulhouse to Lyon on November 22
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Gare routière de Mulhouse
Lyon - Perrache Bus Station
CheapestFastest
Next departures for Mulhouse to Lyon on November 24
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Gare routière de Mulhouse
Lyon - Perrache Bus Station
CheapestFastest
Last refresh of the prices: Last Saturday at 5:18 PM CET.
Compare 2 ways to go from Mulhouse to Lyon
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 3 hours 50 minutes and with fares starting at just $22, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11138 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $23
Frequently asked questions about traveling from Mulhouse to Lyon by bus
How far is Mulhouse from Lyon?
About 182 miles (293 km) separate Mulhouse and Lyon.
What are the departure and arrival stations when taking the bus from Mulhouse to Lyon?
Most of the buses traveling from Mulhouse to Lyon leave from Gare routière de Mulhouse and arrive at Perrache. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Lyon?
Once in Lyon, you can start exploring the city and discover its surroundings. The top sights and things to do are The Old Town, La Place des Terreaux/Bartholdi Fountain, Institut Lumière, Aquarium Grand Lyon and Musée d’Art Contemporain.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$38
11/18
$39
Today
$35
11/20
$22
11/21
$28
11/22
$28
11/23
$24
11/24
$24
The cheapest trip from Mulhouse to Lyon was searched and found on Nov 20, 2025 with a price of $22
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mulhouse to Lyon, as early as possible.
You can expect to pay from $22 to $42 for a bus ticket from Mulhouse to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $22 which is on 2025-11-20.
The cheapest trip from Mulhouse to Lyon was searched and found on Nov 20, 2025 with a price of $22
