What is the distance between Medford and Los Angeles?

The distance separating Medford and Los Angeles is 622 miles (1003 km).

What are the departure and arrival stations when taking the bus from Medford to Los Angeles?

If you're headed to Los Angeles from Medford, chances are that your bus will leave from Front Street Station and arrive at UCLA. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Los Angeles?

Once in Los Angeles, you can start exploring the city and discover its surroundings. The top sights and things to do are Norton Simon Museum, Griffith Park, Sunset Strip, Rose Bowl Loop and Venice Beach.

Bus Medford to Los Angeles from $221 | Refundable Tickets

Next departures

Next departures for Medford to Los Angeles on November 22
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
4:40pm	Front Street Station	1d 4h	9:11pm	Union Station	Cheapest
5:50pm	MFR Airport	1d 3h	9:11pm	Union Station	Fastest
4:40pm	Front Street Station	1d 4h	9:11pm	Union Station	No tags
5:50pm	MFR Airport	1d 3h	9:11pm	Union Station	No tags

Last refresh of the prices: Today at 6:48 PM PST.

Get from Medford to Los Angeles

This route is served by bus only

The journey takes about 21 hours and with fares starting at just $96, it presents an excellent value for a comfortable ride.

5bus per day

21hAverage Duration

616 milesDistance

25kgCO₂ emissions

Compare bus companies

Amtrak

4/55,594 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Greyhound

3.5/587,383 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Fronteras del Norte

3.5/53 reviews

Staff5

Timeliness1.7

Cleanliness5

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Medford and Los Angeles?

Stops in Medford

A - Front Street Station

B - Medford Airport

Stops in Los Angeles

A - UCLA

B - Ramirez Street bus stop

C - 613 Maple Ave

D - Los Angeles International Airport

E - Downtown Westin Bonaventure

F - LAX Airport Holiday Inn

Frequently asked questions about traveling from Medford, OR to Los Angeles, US by bus

What is the distance between Medford and Los Angeles?
What are the departure and arrival stations when taking the bus from Medford to Los Angeles?
What are the best sights and things to do in Los Angeles?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/17

$134

11/18

$162

Today

No data

11/20

$221

11/21

No data

11/22

$276

11/23

$276

11/24

No data

The cheapest trip from Medford, OR to Los Angeles, US was searched and found on Nov 17, 2025 with a price of $134

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medford, OR to Los Angeles, US, as early as possible.

You can expect to pay from $134 to $737 for a bus ticket from Medford, OR to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $221 which is on 2025-11-20.