Among the sustainable travel choices, the bus stands out as the good way to reach Madrid. The journey takes about 19 hours 25 minutes and with fares starting at just $36, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11142 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $55
Based on 60786 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. ALSA ticket prices on this trip start at $136
ALSA Lyon Madrid recent customer reviews
Loved that there were screens to watch movies during the travel time. However we were quite delayed arriving in Madrid, making it difficult to use the time necessary for activities that were planned.
4 out of 5 stars
Veronica Ines Y.
There needs to be someone that lets passengers know that the bus is running late so we can attempt to make other plans. I missed work, because my bus was three hours late.
Based on 1946 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the departure location but often complained with the wifi. Union Ivkoni ticket prices on this trip start at $36
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain
F - Ronda de Valencia 6
Ronda de Valencia 6, 28012 Madrid, Spain
Frequently asked questions about traveling from Lyon to Madrid by bus
What is the travel distance from Lyon to Madrid?
The distance between the two cities is 567 miles (914 km).
What are the departure and arrival stations when taking the bus from Lyon to Madrid?
The majority of buses traveling from Lyon to Madrid start their journey at Lyon Airport and wind up at Estación Sur. These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Madrid?
Once in Madrid, you can start exploring the city and discover its surroundings. The top sights and things to do are Teleférico de Madrid, Puerta del Sol, Faro de Moncloa, Palacio Real and Flamenco.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$183
11/18
$201
Today
$131
11/20
$84
11/21
$55
11/22
$55
11/23
$47
11/24
$55
The cheapest trip from Lyon to Madrid was searched and found on Nov 23, 2025 with a price of $47
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Madrid, as early as possible.
You can expect to pay from $47 to $201 for a bus ticket from Lyon to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-11-23.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Lyon to Madrid?
The bus is the cheapest travel choice for this destination