What is the travel distance from Lyon to Frankfurt am Main?

About 350 miles (564 km) separate Lyon and Frankfurt am Main.

What are the departure and arrival stations when taking the bus from Lyon to Frankfurt am Main?

The majority of buses traveling from Lyon to Frankfurt am Main start their journey at Perrache and wind up at Hbf. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.

Bus Lyon to Frankfurt am Main from $34 | Refundable Tickets

Next departures

Next departures for Lyon to Frankfurt am Main on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		2:10am	Lyon - Perrache Bus Station	11h 10m	1:20pm	Frankfurt - Main bus station	Cheapest
		2:10am	Lyon - Perrache Bus Station	10h 45m	12:55pm	Frankfurt Main Airport P36	Fastest

Next departures for Lyon to Frankfurt am Main on November 15
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:25am	Lyon - Perrache Bus Station	10h 45m	2:10pm	Frankfurt - Main bus station	Cheapest
	2:25am	Perrache	10h	12:25pm	Frankfurt Hbf	Fastest
	9:50am	de Perrache - Galerie A	10h 10m	8:00pm	Hbf	No tags
	2:10am	Lyon - Perrache Bus Station	11h 10m	1:20pm	Frankfurt - Main bus station	No tags
	5:05pm	Aéroport LYS	12h 25m	5:30am	FRA Frankfurt airport	No tags
Flixbus + Flixtrain	5:05pm	Aéroport LYS	18h 2m	11:07am	Südbahnhof	No tags
	9:50am	Perrache	10h 10m	8:00pm	Hbf	No tags
	7:30pm	Aéroport LYS	14h 50m	10:20am	FRA Frankfurt airport	No tags

Next departures for Lyon to Frankfurt am Main on November 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		3:25am	Lyon - Perrache Bus Station	10h 45m	2:10pm	Frankfurt - Main bus station	Cheapest
		3:25am	Lyon - Perrache Bus Station	10h 20m	1:45pm	Frankfurt Main Airport P36	Fastest

Next departures for Lyon to Frankfurt am Main on November 17
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	2:25am	Perrache	10h	12:25pm	Frankfurt Hbf	CheapestFastest
	9:50am	de Perrache - Galerie A	10h 10m	8:00pm	Hbf	No tags
	2:10am	Lyon - Perrache Bus Station	11h 10m	1:20pm	Frankfurt - Main bus station	No tags
	5:05pm	Aéroport LYS	16h 5m	9:10am	FRA Frankfurt airport	No tags
Flixbus + Flixtrain	5:05pm	Aéroport LYS	19h 30m	12:35pm	Südbahnhof	No tags
	9:50am	Perrache	10h 10m	8:00pm	Hbf	No tags
	7:30pm	Aéroport LYS	14h 50m	10:20am	FRA Frankfurt airport	No tags
Flixbus + Flixtrain	11:00pm	Perrache	13h 35m	12:35pm	Südbahnhof	No tags

Last refresh of the prices: Last Monday at 11:07 AM CET.

Compare 3 ways to go from Lyon to Frankfurt am Main

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Frankfurt am Main. The journey takes about 6 hours 20 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.

1carpool per day

6h 20mAverage Duration

350 milesDistance

24kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$39 - $169	Average Duration12h 25m	CO₂ emissions 14kg CO₂e
Train	Average Price$84 - $352	Average Duration6h 55m	CO₂ emissions 13kg CO₂e
Carpool	Average Price$50 - $62	Average Duration6h 20m	CO₂ emissions 24kg CO₂e

Compare bus companies

FlixBus

3.5/511,293 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

BlaBlaCar Bus

3.5/511,112 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

Sindbad

3.5/51,199 reviews

Staff4.2

Timeliness3.4

Cleanliness4.4

Wifi2.5

DE bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Lyon and Frankfurt am Main?

Stops in Lyon

A - Perrache

B - Lyon Airport

C - Lyon

D - Quai de Saoune

E - Villeurbanne INSA

F - Les Charrières

Stops in Frankfurt am Main

A - Hbf

B - Frankfurt Airport

C - Südbahnhof

D - Frankfurt Onibus

E - Braubachstraße 41

F - Flughafen Hahn Airport (HHN)

Frequently asked questions about traveling from Lyon to Frankfurt am Main by bus

What is the travel distance from Lyon to Frankfurt am Main?
What are the departure and arrival stations when taking the bus from Lyon to Frankfurt am Main?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/11

$54

11/12

$41

Today

$66

11/14

$41

11/15

$36

11/16

$36

11/17

$38

11/18

$36

The cheapest trip from Lyon to Frankfurt am Main was searched and found on Nov 18, 2025 with a price of $36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Frankfurt am Main, as early as possible.

You can expect to pay from $36 to $86 for a bus ticket from Lyon to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-11-18.

Usually Sindbad will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.