What is the distance between Lugano and Brussels?

The distance separating Lugano and Brussels is 396 miles (638 km).

What are the departure and arrival stations when taking the bus from Lugano to Brussels?

If you're headed to Brussels from Lugano, chances are that your bus will leave from Arrêt D'autobus Lugano and arrive at Brussels South (Gare du Midi). These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Brussels?

Once in Brussels, you can start exploring the city and discover its surroundings. The top sights and things to do are Pride Festival in Brussels, Le Tour - Brussels Grand Départ, Bright Brussels Festival, 20km of Brussels - 36 years of Brussels' most popular race and Visit the Laeken Royal Greenhouses in Brussels.

Bus Lugano to Brussels from $50 | Refundable Tickets

Previously seen trips

Next departures for Lugano to Brussels on November 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:10pm	Arrêt D'autobus Lugano	11h 20m	8:30am	Brussels-South (Gare du Midi)	No tags
Bus	10:55pm	Lugano	19h 10m	6:05pm	Brussels-North (Gare du Nord)	No tags
Bus	10:55pm	Lugano	1d 1h	12:40am	Brussels Airport	No tags
Bus	11:10pm	Lugano	20h 15m	7:25pm	Brussels-North (Gare du Nord)	No tags
Bus	11:10pm	Lugano	1d 8h	7:20am	Brussels South (Gare du Midi)	No tags

Compare 2 ways to go from Lugano to Brussels

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 9 hours 10 minutes and with fares starting at just $80, it presents an excellent value for a comfortable ride.

1carpool per day

9h 10mAverage Duration

395 milesDistance

27kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$54 - $209	Average Duration20h	CO₂ emissions 16kg CO₂e
Carpool	Average Price$80 - $80	Average Duration9h 10m	CO₂ emissions 27kg CO₂e

Where are the popular stops in Lugano and Brussels?

Stops in Lugano

A
Arrêt D'autobus Lugano
Via Giacomo E Filippo Ciani, 6900 Lugano, Switzerland
Visit page
B
Stazione/Gare de Lugano
Stazione FFS 1, 6900 Lugano, Switzerland
C
Via Basilea
Via Basilea, 6900 Lugano, Switzerland

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Compare bus companies

FlixBus

3.5/511,388 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

BlaBlaCar Bus

3.5/511,143 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

BE bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Lugano to Brussels by bus

What is the distance between Lugano and Brussels?
What are the departure and arrival stations when taking the bus from Lugano to Brussels?
What are the best sights and things to do in Brussels?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/19

$56

11/20

$58

Today

$50

11/22

No data

11/23

$54

11/24

No data

11/25

No data

11/26

No data

The cheapest trip from Lugano to Brussels was searched and found on Nov 21, 2025 with a price of $50

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lugano to Brussels, as early as possible.

You can expect to pay from $50 to $205 for a bus ticket from Lugano to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2025-11-23.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.