Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Louisville, KY | Wheeling Bus Stop | Cheapest | ||||
 | Bus | Louisville, KY | Wheeling Bus Stop | Fastest |
Last refresh of the prices: Today at 1:46 PM EST.
Get from Louisville to Wheeling
The journey takes about 13 hours 30 minutes and with fares starting at just $145, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Louisville to Wheeling by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Louisville to Wheeling?
The cheapest bus tickets from Louisville to Wheeling start from $145. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Louisville to Wheeling?
The average bus trip duration from Louisville to Wheeling is 13h 30m, covering a distance of 298 miles (480 km). The quickest bus can get you there in 13h 30m and is operated by Greyhound.
Which bus companies service the Louisville to Wheeling route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Louisville to Wheeling?
The earliest bus departs from Louisville to Wheeling at 2:50am. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Louisville to Wheeling?
A bus trip from Louisville to Wheeling generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Wheeling was searched and found on Jan 16, 2026 with a price of $109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Wheeling, as early as possible.
You can expect to pay from $109 to $109 for a bus ticket from Louisville to Wheeling based on the last 2 days. You can expect to find the cheapest price for the trip at $109 which is on 2026-01-16.
