What is the distance between Lexington and Knoxville?

Lexington and Knoxville are 146 miles (235 km) apart.

What are the departure and arrival stations when taking the bus from Lexington to Knoxville?

If you're headed to Knoxville from Lexington, chances are that your bus will depart from WJW Investments Bus Stop and arrive at 100 Kirkwood St. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus Lexington to Knoxville from $34 | Refundable Tickets

Previously seen trips

Next departures for Lexington to Knoxville on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:50pm	WJW Investments Bus Stop	3h 35m	6:25pm	Knoxville Bus Station	No tags
Bus	3:15pm	WJW Investments Bus Stop	3h 40m	6:55pm	Knoxville Bus Station	No tags
Bus	3:15pm	WJW Investments Bus Stop	3h 40m	6:55pm	Knoxville Bus Station	No tags
Bus	3:15pm	WJW Investments Bus Stop	3h 40m	6:55pm	Knoxville Bus Station	No tags
Bus	3:15pm	WJW Investments Bus Stop	3h 40m	6:55pm	Knoxville Bus Station	No tags

Get from Lexington to Knoxville

This route is served by bus only

The journey takes about 3 hours 45 minutes and with fares starting at just $42, it presents an excellent value for a comfortable ride.

1bus per day

3h 45mAverage Duration

147 milesDistance

6kgCO₂ emissions

Where are the popular stops in Lexington and Knoxville?

Stops in Lexington

A
WJW Investments Bus Stop
477 W New Circle Rd, Lexington, KY 40511
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B
Bus Stop Lexington
1801 Alexandria Dr, Lexington, KY 40504, USA
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Stops in Knoxville

A
100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
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Compare bus companies

Greyhound

3.5/587,391 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Lexington, KY to Knoxville, TN by bus

What is the distance between Lexington and Knoxville?
What are the departure and arrival stations when taking the bus from Lexington to Knoxville?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

No data

11/22

$57

Today

No data

11/24

$40

11/25

No data

11/26

No data

11/27

No data

11/28

No data

The cheapest trip from Lexington, KY to Knoxville, TN was searched and found on Nov 24, 2025 with a price of $40

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lexington, KY to Knoxville, TN, as early as possible.

You can expect to pay from $40 to $57 for a bus ticket from Lexington, KY to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2025-11-24.