Next departures for Kissimmee to Jacksonville on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
E Osceola Pkwy
Jacksonville Bus Station
CheapestFastest
Next departures for Kissimmee to Jacksonville on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
E Osceola Pkwy
Jacksonville Bus Station
CheapestFastest
Bus
E Osceola Pkwy
Jacksonville Bus Station
No tags
Last refresh of the prices: Today at 7:09 AM EST.
Compare 2 ways to go from Kissimmee to Jacksonville
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Jacksonville. The journey takes about 3 hours 55 minutes and with fares starting at just $33, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
The Best - this guy knew his stuff. He has the personality to avoid conflicts and stays focussed on the mission to arrive destination safely and securely. He gave us specific information and directions to interconnections. He was extremely helpful with everything. Very courteous. Very explicit and alert. Manner and answered all questions from others on the bus.
5 out of 5 stars
Nancy V.
Needs more space for better rides
4 out of 5 stars
Axel R.
Greyhound office at Kissimmee was closed an unable to retrieve printed ticket
Frequently asked questions about traveling from Kissimmee to Jacksonville, FL by bus
What is the distance between Kissimmee and Jacksonville?
The distance separating Kissimmee and Jacksonville is 141 miles (227 km).
What are the departure and arrival stations when taking the bus from Kissimmee to Jacksonville?
If you're headed to Jacksonville from Kissimmee, chances are that your bus will leave from E Osceola Pkwy and arrive at Jacksonville Amtrak Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$42
11/22
$40
Today
$43
11/24
$34
11/25
$37
11/26
$40
11/27
$34
11/28
$35
The cheapest trip from Kissimmee to Jacksonville, FL was searched and found on Nov 24, 2025 with a price of $34
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Kissimmee to Jacksonville, FL, as early as possible.
You can expect to pay from $34 to $56 for a bus ticket from Kissimmee to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $34 which is on 2025-11-24.
The cheapest trip from Kissimmee to Jacksonville, FL was searched and found on Nov 24, 2025 with a price of $34
