What is the distance between Jacksonville and Port Saint Lucie?

About 225 miles (362 km) separate Jacksonville and Port Saint Lucie.

What are the departure and arrival stations when taking the bus from Jacksonville to Port Saint Lucie?

If you're headed to Port Saint Lucie from Jacksonville, chances are that your bus will leave from Jacksonville Amtrak Station and arrive at Port St Lucie Mobil Gas Bus Stop. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Jacksonville to Port Saint Lucie from $37 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to Port Saint Lucie on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	9:10pm	Jacksonville Bus Station	6h 5m	3:15am	Port St. Lucie (Park & Ride)	CheapestFastest
	Bus	1:50pm	Jacksonville Bus Station	11h 45m	1:35am	Port St. Lucie (Park & Ride)	No tags

Last refresh of the prices: Yesterday at 4:42 PM EST.

Get from Jacksonville to Port Saint Lucie

This route is served by bus only

The journey takes about 6 hours 40 minutes and with fares starting at just $42, it presents an excellent value for a comfortable ride.

2bus per day

6h 40mAverage Duration

225 milesDistance

9kgCO₂ emissions

Where are the popular stops in Jacksonville and Port Saint Lucie?

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in Port Saint Lucie

A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986
Visit page
B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986
C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA
D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953

Compare bus companies

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,396 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Jacksonville, FL to Port Saint Lucie by bus

What is the distance between Jacksonville and Port Saint Lucie?
What are the departure and arrival stations when taking the bus from Jacksonville to Port Saint Lucie?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

$56

11/25

$69

Today

$118

11/27

No data

11/28

No data

11/29

No data

11/30

No data

12/01

No data

The cheapest trip from Jacksonville, FL to Port Saint Lucie was searched and found on Nov 24, 2025 with a price of $56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Port Saint Lucie, as early as possible.