Next departures for Harrisburg to Boston on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Harrisburg Bus Station
Boston (South Station)
Cheapest
Bus
Harrisburg Bus Station
Boston (South Station)
Fastest
Next departures for Harrisburg to Boston on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Harrisburg Bus Station
Boston (South Station)
Cheapest
Bus
Harrisburg Bus Station
Boston (South Station)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Next departures for Harrisburg to Boston on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Brookline
Cheapest
Bus
Harrisburg Bus Station
Boston (South Station)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Next departures for Harrisburg to Boston on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
Cheapest
Bus
Harrisburg Bus Station
Boston (South Station)
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Next departures for Harrisburg to Boston on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Harrisburg Bus Station
Boston (South Station)
CheapestFastest
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Bus
Harrisburg Bus Station
Boston (South Station)
No tags
Last refresh of the prices: Yesterday at 8:57 PM EST.
Compare 2 ways to go from Harrisburg to Boston
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 10 hours 55 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $156
Frequently asked questions about traveling from Harrisburg to Boston, MA, US by bus
How far is Harrisburg from Boston?
The distance separating Harrisburg and Boston is 335 miles (540 km).
What are the departure and arrival stations when taking the bus from Harrisburg to Boston?
Most of the buses traveling from Harrisburg to Boston leave from Harrisburg Bieber Greyhound Station and arrive at Back Bay Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Boston?
Once in Boston, you can start exploring the city and discover its surroundings. The top sights and things to do are Boston Open Studios, Boston Blazers at TD Garden, JFK Library, Duck Tour and Boston Public Library.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$145
11/25
$119
Today
$164
11/27
$130
11/28
$93
11/29
$142
11/30
$199
12/01
$83
The cheapest trip from Harrisburg to Boston, MA, US was searched and found on Dec 1, 2025 with a price of $83
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Boston, MA, US, as early as possible.
You can expect to pay from $83 to $230 for a bus ticket from Harrisburg to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-12-01.
What's the cheapest way to go from Harrisburg to Boston, MA, US?
The bus is the cheapest travel choice for this destination