How far is Greenville from Wilmington?

The distance between the two cities is 504 miles (813 km).

What are the departure and arrival stations when taking the bus from Greenville to Wilmington?

Most of the buses traveling from Greenville to Wilmington leave from Guadalajara Supermarket Bus Stop and arrive at Wilmington Bus Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus Greenville to Wilmington from $114 | Refundable Tickets

Previously seen trips

Next departures for Greenville to Wilmington on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:50am	1116 Woodruff Rd	19h 5m	5:55am	Wilmington Bus Station	No tags
Greyhound + FlixBus	Bus	12:15pm	1116 Woodruff Rd	17h 40m	5:55am	Wilmington Bus Station	No tags
Greyhound + FlixBus	Bus	4:35pm	1116 Woodruff Rd	17h 15m	9:50am	Wilmington Bus Station	No tags
FlixBus + Greyhound	Bus	4:35pm	1116 Woodruff Rd	17h 15m	9:50am	Wilmington Bus Station	No tags
FlixBus + Greyhound	Bus	10:15pm	1116 Woodruff Rd	15h 25m	1:40pm	Wilmington Bus Station	No tags

Compare 2 ways to go from Greenville to Wilmington

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Wilmington. The journey takes about 14 hours 19 minutes and with fares starting at just $127, it presents an excellent value for a comfortable ride.

1train per day

14h 19mAverage Duration

505 milesDistance

74kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$82 - $304	Average Duration18h 45m	CO₂ emissions 20kg CO₂e
Train	Average Price$127 - $1,091	Average Duration14h 19m	CO₂ emissions 74kg CO₂e

Where are the popular stops in Greenville and Wilmington?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Wilmington Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Compare bus companies

FlixBus

3.5/511,439 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Greenville, SC to Wilmington, DE by bus

How far is Greenville from Wilmington?
What are the departure and arrival stations when taking the bus from Greenville to Wilmington?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

No data

11/23

$158

Today

$167

11/25

$175

11/26

$116

11/27

No data

11/28

No data

11/29

$118

The cheapest trip from Greenville, SC to Wilmington, DE was searched and found on Nov 26, 2025 with a price of $116

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Wilmington, DE, as early as possible.

You can expect to pay from $116 to $296 for a bus ticket from Greenville, SC to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at $116 which is on 2025-11-26.