Bus from Greenville, SC to Pittsburgh: Tickets & Schedules

Next bus departures

Next departures for Greenville to Pittsburgh on December 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
Pittsburgh Intermodal StationCheapestFastest

Last refresh of the prices: Yesterday at 10:35 AM EST.

Compare 2 ways to go from Greenville to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 18 hours and with fares starting at just $113, it presents an excellent value for a comfortable ride.

3bus per day
18hAverage Duration
408 milesDistance
16kgCO₂ emissions
Average Price$113 - $424Average Duration18h
16kg CO₂e
Average Price$171 - $1,113Average Duration21h 17m
60kg CO₂e

Frequently asked questions about traveling from Greenville, SC to Pittsburgh by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Pittsburgh?

    The cheapest bus tickets from Greenville to Pittsburgh start from $113. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Pittsburgh?

    The average bus trip duration from Greenville to Pittsburgh is 18h, covering a distance of 408 miles (657 km). The quickest bus can get you there in 17h 5m and is operated by FlixBus.

  3. Which bus companies service the Greenville to Pittsburgh route?

    Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Greenville to Pittsburgh?

    The earliest bus departs from Greenville to Pittsburgh at 10:50am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Pittsburgh?

    A bus trip from Greenville to Pittsburgh generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to Pittsburgh?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11648 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Pittsburgh?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Greenville to Pittsburgh?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Pittsburgh?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/27
No data
12/28
No data
Today
$127
12/30
No data
12/31
No data
busbud logoThe cheapest trip from Greenville, SC to Pittsburgh was searched and found on Dec 29, 2025 with a price of $127

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh, as early as possible.

What's the cheapest way to go from Greenville, SC to Pittsburgh?

busbud logoThe bus is the cheapest travel choice for this destination

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