Bus from Greenville, SC to Birmingham, US: Tickets & Schedules

Next bus departures

Next departures for Greenville to Birmingham on December 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
Birmingham Greyhound Bus StationCheapest
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
Birmingham Greyhound Bus StationFastest
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
Birmingham Greyhound Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
Birmingham Greyhound Bus StationNo tags

Last refresh of the prices: Yesterday at 4:02 AM EST.

Compare 2 ways to go from Greenville to Birmingham

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Birmingham. The journey takes about 7 hours 15 minutes and with fares starting at just $45, it presents an excellent value for a comfortable ride.

7bus per day
7h 15mAverage Duration
273 milesDistance
11kgCO₂ emissions
Average Price$45 - $169Average Duration7h 15m
11kg CO₂e
Average Price$70 - $123Average Duration8h 14m
39kg CO₂e

Frequently asked questions about traveling from Greenville, SC to Birmingham, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Birmingham?

    The cheapest bus tickets from Greenville to Birmingham start from $45. The average price for this route is around $77. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Birmingham?

    The average bus trip duration from Greenville to Birmingham is 7h 15m, covering a distance of 273 miles (440 km). The quickest bus can get you there in 5h 50m and is operated by FlixBus.

  3. Which bus companies service the Greenville to Birmingham route?

    Several major bus companies operate on this route with 7 buses available per day, including services from Tornado Bus, Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Greenville to Birmingham?

    The earliest bus departs from Greenville to Birmingham at 7:40am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Birmingham?

    A bus trip from Greenville to Birmingham generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to Birmingham?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Birmingham?

    Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company has the most timely service from Greenville to Birmingham?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Birmingham?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/29
$66
11/30
No data
Today
$131
12/02
No data
12/03
$53
12/04
$41
12/05
$46
12/06
$50
busbud logoThe cheapest trip from Greenville, SC to Birmingham, US was searched and found on Dec 4, 2025 with a price of $41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Birmingham, US, as early as possible.

You can expect to pay from $41 to $150 for a bus ticket from Greenville, SC to Birmingham, US based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-12-04.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Greenville, SC to Birmingham, US?

busbud logoThe bus is the cheapest travel choice for this destination

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