Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gainesville (Mart 24/7) | Downtown Greyhound Station | CheapestFastest | ||||
| Bus | Gainesville (Mart 24/7) | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gainesville (Mart 24/7) | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 8:04 AM EST.
Compare 2 ways to go from Gainesville to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 19 hours 40 minutes and with fares starting at just $128, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Chicago?
Stops in Gainesville
- A
La Flor de Jalisco Bus Stop
425 Atlanta Hwy, Gainesville, GA 30501 - B
Gainesville Bus Station Mart 24/7
2580 MONROE DRIVE , 30507, Georgia - C
El Expreso Gainesville Bus Stop
1408 Atlanta Hwy, Gainesville, GA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Gainesville Chicago recent customer reviews
The driver literally lied to me. He told there is another bus from Gainesville to atlanta behind him. But after waiting for 3 hr in cold outside, I called greyhound and there was no bus. I had to leave by means from Gainesville to atlanta so I took the uber from from gainsville to atlanta which cost me a lot and was able to catch my next transfer in atlanta. I was wondering do the greyhound pay for the compensation
Prem S.
Frequently asked questions about traveling from Gainesville, GA to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Chicago?
The cheapest bus tickets from Gainesville to Chicago start from $128. The average price for this route is around $170. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Chicago?
The average bus trip duration from Gainesville to Chicago is 19h 40m, covering a distance of 554 miles (893 km). The quickest bus can get you there in 17h 50m and is operated by Greyhound.
Which bus companies service the Gainesville to Chicago route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Gainesville to Chicago?
The earliest bus departs from Gainesville to Chicago at 10:20pm. And the latest bus departs at 10:25pm.
What are the CO₂ emissions for the bus trip from Gainesville to Chicago?
A bus trip from Gainesville to Chicago generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, GA to Chicago was searched and found on Dec 25, 2025 with a price of $130To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, GA to Chicago, as early as possible.
You can expect to pay from $130 to $315 for a bus ticket from Gainesville, GA to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2025-12-25.
What's the cheapest way to go from Gainesville, GA to Chicago?
The bus is the cheapest travel choice for this destination
