How do I get from Florence to Syracuse without flying?

Taking the bus is the best way to travel to Syracuse without flying. The bus trip is an affordable, safe and convenient way to travel between the two cities. You also have the option of using carpooling services.

How long is the bus ride from Florence to Syracuse?

The average travel time from Florence to Syracuse is about 19h 15m, but you can get there in as little as 15h 40m with the quickest bus. This is the time it takes to travel the 509 miles (820 km) that separate the two cities.

How far is Florence from Syracuse?

Florence and Syracuse are 509 miles (820 km) apart.

What are the departure and arrival stations when taking the bus from Florence to Syracuse?

Most of the buses traveling from Florence to Syracuse leave from Florence - Piazzale Montelungo and arrive at Fermata dell'autobus Siracusa. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What is the cheapest way to travel from Florence to Syracuse?

The cheapest way to travel this route is by bus. The lowest tickets for this trip cost as little as $59.

How much does a bus ticket from Florence to Syracuse cost?

The bus ticket costs $113 on average. In the last 30 days, the prices ranged from $59 to $186, so it's good to do your research before booking.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Webster Pond, Erie Canal Museum, Oncenter War Memorial Arena, Onondaga Historical Association Museum and Landmark Theatre.

Can I take an overnight bus from Florence to Syracuse?

Certainly! You can indeed opt for an overnight bus from Florence to Syracuse. Make sure to pack a blanket and a snack to make your trip more comfortable.

Florence to Syracuse Bus Tickets

TodayMay 24

from $94

TomorrowMay 25

from $99

MonMay 26

TueMay 27

WedMay 28

ThuMay 29

FriMay 30

SatMay 31

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: May 25 at 5:55pm
Departure city: Florence
Departure location: Florence (Villa Costanza)
Arrival time: May 26 at 9:35am
Destination city: Syracuse
Destination location: Terminal Interbus
Operated by: Flixbus
Vehicle: BusDuration: 15h 40m
Departure time: May 25 at 1:00am
Departure city: Florence
Departure location: Florence (Villa Costanza)
Arrival time: May 25 at 8:40pm
Destination city: Syracuse
Destination location: Terminal Interbus
Operated by: Flixbus
Vehicle: BusDuration: 19h 40m
Departure time: May 25 at 11:10pm
Departure city: Florence
Departure location: Florence (Villa Costanza)
Arrival time: May 26 at 8:40pm
Destination city: Syracuse
Destination location: Terminal Interbus
Operated by: Flixbus
Vehicle: BusDuration: 21h 30m
Departure time: May 25 at 1:25am
Departure city: Florence
Departure location: Viale Filippo Strozzi
Arrival time: May 25 at 8:40pm
Destination city: Syracuse
Destination location: Terminal Interbus
Operated by: Flixbus
Vehicle: BusDuration: 19h 15m

Accepted payments

Bus Florence to Syracuse: Trip Overview

Average ticket price$113

Average bus trip duration19h 15m

Number of daily buses2

Earliest bus departure1:00am

Distance510 miles (821 km)

Latest bus departure11:10pm

Compare bus companies

FlixBus

3.5/58,733 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Trenitalia, Sindbad, MarinoBus, Infobus

Florence to Syracuse Bus

Busbud helps you find a bus from Florence to Syracuse. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Syracuse.

From cheap bus tickets to more luxurious buses traveling from Florence to Syracuse, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Florence and Syracuse?

Stops in Florence

A - Florence - Piazzale Montelungo

B - Terminal Bus Villa Constanza

C - Florence Airport

D - Scandicci - Villa Costanza

E - Santa Maria Novella

F - Via Cassia, 49B

Stops in Syracuse

A - Fermata dell'autobus Siracusa

B - Siracusa

C - Siracusa - Terminal Bus (Stazione FS)

Frequently asked questions for your trip Florence - Syracuse

How do I get from Florence to Syracuse without flying?
How long is the bus ride from Florence to Syracuse?
How far is Florence from Syracuse?
What are the departure and arrival stations when taking the bus from Florence to Syracuse?
What is the cheapest way to travel from Florence to Syracuse?
How much does a bus ticket from Florence to Syracuse cost?
What are the best sights and things to do in Syracuse?
Can I take an overnight bus from Florence to Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/22

$38

05/23

No data

Today

$88

05/25

$93

05/26

No data

05/27

No data

05/28

No data

05/29

No data

The cheapest trip from Florence to Syracuse was searched and found on May 22, 2025 with a price of $38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Syracuse, as early as possible.

You can expect to pay from $38 to $142 for a bus ticket from Florence to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $93 which is on 2025-05-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Syracuse!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Syracuse.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Syracuse that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Syracuse.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Florence by bus?

Bus from Florence to Syracuse

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Bus Tickets from Florence to Syracuse

One passenger / one way

Cheap buses leaving tomorrow

One passenger / one way

Bus Florence to Syracuse: Trip Overview

Compare bus companies

Florence to Syracuse Bus

Where are the popular stops in Florence and Syracuse?

Frequently asked questions for your trip Florence - Syracuse

How do I get from Florence to Syracuse without flying?

How long is the bus ride from Florence to Syracuse?

How far is Florence from Syracuse?

What are the departure and arrival stations when taking the bus from Florence to Syracuse?

What is the cheapest way to travel from Florence to Syracuse?

How much does a bus ticket from Florence to Syracuse cost?

What are the best sights and things to do in Syracuse?

Can I take an overnight bus from Florence to Syracuse?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Florence by bus?

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

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