What is the distance between Florence and Palermo?

About 406 miles (654 km) separate Florence and Palermo.

What are the departure and arrival stations when taking the bus from Florence to Palermo?

If you're headed to Palermo from Florence, chances are that your bus will leave from Terminal Bus Villa Constanza and arrive at Terminal Bus Palermo. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Palermo?

Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Cattedrale di Palermo, Palazzo dei Normanni, Galleria Regionale della Sicilia, Cappella Palatina and Orto Botanico.

Bus Florence to Palermo from $42 | Refundable Tickets

Next bus departures

Next departures for Florence to Palermo on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	5:55pm	Florence (Villa Costanza)	20h 30m	2:25pm	Terminal Bus Palermo	Cheapest
Bus	10:00pm	Florence (Villa Costanza)	16h 25m	2:25pm	Terminal Bus Palermo	Fastest
Bus	5:55pm	Florence (Villa Costanza)	17h 5m	11:00am	Terminal Bus Palermo	No tags

Next departures for Florence to Palermo on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	5:55pm	Florence (Villa Costanza)	20h 30m	2:25pm	Terminal Bus Palermo	Cheapest
Bus	3:45pm	Terminal Bus Villa Constanza	16h	7:45am	Terminal Bus Palermo	Fastest
Bus	5:55pm	Florence (Villa Costanza)	17h 5m	11:00am	Terminal Bus Palermo	No tags
Bus	10:00pm	Florence (Villa Costanza)	16h 25m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Florence to Palermo on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:45pm	Terminal Bus Villa Constanza	16h	7:45am	Terminal Bus Palermo	CheapestFastest

Last refresh of the prices: Last Friday at 1:27 PM CET.

Compare 2 ways to go from Florence to Palermo

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Palermo. The journey takes about 16 hours 25 minutes and with fares starting at just $28, it presents an excellent value for a comfortable ride.

2bus per day

16h 25mAverage Duration

406 milesDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$28 - $190	Average Duration16h 25m	CO₂ emissions 16kg CO₂e
Carpool	Average Price$116 - $116	Average Duration13h	CO₂ emissions 27kg CO₂e

Where are the popular stops in Florence and Palermo?

Stops in Florence

A
Terminal Bus Villa Constanza
A1 - Autostrada del Sole, 50018 Scandicci FI, Italy
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B
Florence - Piazzale Montelungo
50129 Centro Storico FI, Italy
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C
Florence Airport
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D
Scandicci - Villa Costanza
Via della Costituzione, 185, 50018 Scandicci FI, Italy
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E
Santa Maria Novella
Piazza della Stazione 45, 50123 Firenze, Italy
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F
Via Cassia, 49B
Via Cassia, 49B, 50023 Impruneta FI, Italy
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Stops in Palermo

A
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy
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B
Palermo Airport
Punta Raisi, 90145, Palermo
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C
Piazza Cairoli
Piazza Cairoli, 8-14, 90123 Palermo, Italy
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D
Fiera
90143 Palermo PA, Italy
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E
Via Paolo Balsamo, 21
Via Paolo Balsamo, 21, 90123 Palermo, Italy
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F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy

Compare bus companies

FlixBus

3.5/511,411 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Autoservizi Salemi

4.5/5450 reviews

Staff4.9

Timeliness4.3

Cleanliness4.7

Wifi3.9

Itabus

4/5946 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Florence to Palermo by bus

What is the distance between Florence and Palermo?
What are the departure and arrival stations when taking the bus from Florence to Palermo?
What are the best sights and things to do in Palermo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

$35

11/22

$77

Today

$51

11/24

$42

11/25

$44

11/26

$91

11/27

$61

11/28

$98

The cheapest trip from Florence to Palermo was searched and found on Nov 21, 2025 with a price of $35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Palermo, as early as possible.

You can expect to pay from $35 to $103 for a bus ticket from Florence to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2025-11-24.