Next departures for Durham to Tampa on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Durham Greyhound Bus Station
Tampa Bus Station
No tags
Bus
Durham Greyhound Bus Station
University of South Florida
No tags
Greyhound + FlixBus
Bus
Durham Greyhound Bus Station
University of South Florida
No tags
Greyhound + FlixBus
Bus
Durham Greyhound Bus Station
Tampa Bus Station
No tags
FlixBus + Greyhound
Bus
Durham Greyhound Bus Station
Tampa Bus Station
No tags
Compare 2 ways to go from Durham to Tampa
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 19 hours 26 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Durham, NC, US to Tampa by bus
How far is Durham from Tampa?
The distance between the two cities is 594 miles (957 km).
What are the departure and arrival stations when taking the bus from Durham to Tampa?
Most of the buses traveling from Durham to Tampa leave from Durham Greyhound Bus Station and arrive at Tampa 13th Avenue Bus Stop (McDonald's). These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
No data
11/25
No data
Today
$149
11/27
No data
11/28
No data
11/29
No data
11/30
$129
12/01
No data
The cheapest trip from Durham, NC, US to Tampa was searched and found on Nov 30, 2025 with a price of $129
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Tampa, as early as possible.
You can expect to pay from $129 to $165 for a bus ticket from Durham, NC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $129 which is on 2025-11-30.