What is the distance between Durham and Pittsburgh?

The distance between the two cities is 313 miles (505 km).

What are the departure and arrival stations when taking the bus from Durham to Pittsburgh?

If you're headed to Pittsburgh from Durham, chances are that your bus will depart from Durham Greyhound Bus Station and arrive at Intermodal Station. These are the primary departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

Bus Durham to Pittsburgh from $63 | Refundable Tickets

Next bus departures

Next departures for Durham to Pittsburgh on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	5:05pm	Durham Greyhound Bus Station	13h 25m	6:30am	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:15pm	Durham Greyhound Bus Station	13h	10:15am	Pittsburgh Intermodal Station	Fastest

Next departures for Durham to Pittsburgh on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	5:05pm	Durham Greyhound Bus Station	13h 25m	6:30am	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:15pm	Durham Greyhound Bus Station	13h	10:15am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	3:45am	Durham Greyhound Bus Station	14h 5m	5:50pm	Pittsburgh Intermodal Station	No tags
	Bus	9:10am	Durham Greyhound Bus Station	14h 25m	11:35pm	Pittsburgh Intermodal Station	No tags

Next departures for Durham to Pittsburgh on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	3:45am	Durham Greyhound Bus Station	11h 20m	3:05pm	Pittsburgh Intermodal Station	CheapestFastest
	Bus	9:10am	Durham Greyhound Bus Station	14h 25m	11:35pm	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	5:05pm	Durham Greyhound Bus Station	13h 25m	6:30am	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:15pm	Durham Greyhound Bus Station	13h	10:15am	Pittsburgh Intermodal Station	No tags

Next departures for Durham to Pittsburgh on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	3:45am	Durham Greyhound Bus Station	11h 20m	3:05pm	Pittsburgh Intermodal Station	CheapestFastest
	Bus	9:10am	Durham Greyhound Bus Station	14h 25m	11:35pm	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	5:05pm	Durham Greyhound Bus Station	13h 25m	6:30am	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:15pm	Durham Greyhound Bus Station	13h	10:15am	Pittsburgh Intermodal Station	No tags

Last refresh of the prices: Yesterday at 11:06 PM EST.

Compare 2 ways to go from Durham to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 13 hours 25 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

3bus per day

13h 25mAverage Duration

313 milesDistance

13kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$60 - $296	Average Duration13h 25m	CO₂ emissions 13kg CO₂e
Train	Average Price$141 - $1,131	Average Duration1d 5h	CO₂ emissions 46kg CO₂e

Where are the popular stops in Durham and Pittsburgh?

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Durham, NC, US to Pittsburgh by bus

What is the distance between Durham and Pittsburgh?
What are the departure and arrival stations when taking the bus from Durham to Pittsburgh?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

$151

11/24

$157

Today

$200

11/26

$128

11/27

$95

11/28

$98

11/29

$201

11/30

$302

The cheapest trip from Durham, NC, US to Pittsburgh was searched and found on Nov 27, 2025 with a price of $95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Pittsburgh, as early as possible.

You can expect to pay from $95 to $333 for a bus ticket from Durham, NC, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $95 which is on 2025-11-27.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.