Next departures for Durham to Philadelphia on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
Schuylkill & Walnut
No tags
Next departures for Durham to Philadelphia on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Next departures for Durham to Philadelphia on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
Cheapest
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
No tags
Next departures for Durham to Philadelphia on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
Cheapest
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
199 Spring Garden St.
No tags
Bus
Durham Greyhound Bus Station
Philadelphia, 199 Spring Garden St
No tags
Last refresh of the prices: Yesterday at 3:39 PM EST.
Compare 2 ways to go from Durham to Philadelphia
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 9 hours 33 minutes and with fares starting at just $87, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Durham Philadelphia recent customer reviews
The bus was too tight and very late. I would never take Greyhound bus again.
Frequently asked questions about traveling from Durham, NC, US to Philadelphia, PA by bus
How far is Durham from Philadelphia?
The distance between the two cities is 341 miles (550 km).
What are the departure and arrival stations when taking the bus from Durham to Philadelphia?
Most of the buses traveling from Durham to Philadelphia leave from Durham Greyhound Bus Station and arrive at Philadelphia Airport. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Philadelphia Museum of Art, Love Park, The Franklin Institute, Schuylkill River Trail and Arden Theatre Company.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$123
11/22
$112
Today
$127
11/24
$128
11/25
$129
11/26
$138
11/27
$79
11/28
$77
The cheapest trip from Durham, NC, US to Philadelphia, PA was searched and found on Nov 28, 2025 with a price of $77
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Philadelphia, PA, as early as possible.
You can expect to pay from $77 to $264 for a bus ticket from Durham, NC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $77 which is on 2025-11-28.
Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Durham, NC, US to Philadelphia, PA?
The bus is the cheapest travel choice for this destination