Bus Tickets from Durham, NC, US to Buffalo, NY

Next departures

Next departures for Durham to Buffalo on November 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
    		Durham Greyhound Bus Station
    		Buffalo (BUF) AirportCheapest
    FlixBus
      		Durham Greyhound Bus Station
      		Buffalo (BUF) AirportFastest
      FlixBus
        		Durham Greyhound Bus Station
        		Niagara Frontier Transportation AuthorityNo tags
        Greyhound Lines, Inc.
          		Durham Greyhound Bus Station
          		Niagara Frontier Transportation AuthorityNo tags

          Last refresh of the prices: Yesterday at 12:51 AM EST.

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          Compare 2 ways to go from Durham to Buffalo

          We recommend taking the bus

          Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 21 hours 15 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.

          8bus per day
          21h 15mAverage Duration
          475 milesDistance
          19kgCO₂ emissions
          Bus
          		Average Price$105 - $316Average Duration21h 15m
          19kg CO₂e
          Train
          		Average Price$186 - $461Average Duration1d 6h
          70kg CO₂e

          Bus Durham, NC, US to Buffalo, NY: Trip Overview

          Average ticket price$214
          Average bus trip duration21h 15m
          Number of daily buses8
          Earliest bus departure1:20am
          Distance475 miles (766 km)
          Latest bus departure9:15pm

          Durham to Buffalo Bus

          With Busbud, comparing and booking tickets for a bus from Durham to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

          Bus service from Durham to Buffalo will be provided by the most trusted bus companies.

          Discover how much the bus trip from Durham to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

          Frequently asked questions for your trip Durham, NC, US - Buffalo, NY

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          11/02
          $142
          11/03
          No data
          Today
          $137
          11/05
          $126
          11/06
          No data
          11/07
          No data
          11/08
          No data
          11/09
          $106
          busbud logoThe cheapest trip from Durham, NC, US to Buffalo, NY was searched and found on Nov 9, 2025 with a price of $106

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Buffalo, NY, as early as possible.

          You can expect to pay from $106 to $247 for a bus ticket from Durham, NC, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $106 which is on 2025-11-09.

          About Bus Travel

          Bus Travel Tips

          Meet and talk to locals at the bus stations while traveling from Durham to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

          Much more than a mere vehicle taking you from Durham to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

          Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Durham to Buffalo will emit less CO2 than a car or an airplane.

          Make a music playlist for your bus ride from Durham to Buffalo, and enjoy the scenery to tunes from your own personal soundtrack.

          Did you know?

          Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

          9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

          Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

          What's the cheapest way to go from Durham, NC, US to Buffalo, NY?

          busbud logoThe bus is the cheapest travel choice for this destination

          Will you be returning to Durham, NC, US by bus?

          Bus from Buffalo, NY to Durham, NC, US

          You can also go to Buffalo, NY by train

          Train from Durham, NC, US to Buffalo, NY

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