Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 5604 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $236
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Chicago to San Francisco, US by bus
What is the travel distance from Chicago to San Francisco?
The distance between the two cities is 1852 miles (2987 km).
What are the departure and arrival stations when taking the bus from Chicago to San Francisco?
The majority of buses traveling from Chicago to San Francisco start their journey at Downtown Greyhound Station and wind up at Hyde/Beach (Fisherman's Wharf). These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in San Francisco?
Once in San Francisco, you can start exploring the city and discover its surroundings. The top sights and things to do are Aquarium of the Bay, San Francisco Cable Cars, Chinatown, Golden Gate Park and Lombard Street.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
$397
11/23
$484
Today
$251
11/25
$559
11/26
$185
11/27
No data
11/28
No data
11/29
$258
The cheapest trip from Chicago to San Francisco, US was searched and found on Nov 26, 2025 with a price of $185
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Francisco, US, as early as possible.
You can expect to pay from $185 to $584 for a bus ticket from Chicago to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2025-11-26.
The cheapest trip from Chicago to San Francisco, US was searched and found on Nov 26, 2025 with a price of $185
