Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Charleston Bus Station | Wytheville Bus Station | CheapestFastest |
Last refresh of the prices: Today at 12:00 AM EST.
Get from Charleston to Wytheville
The journey takes about 3 hours 25 minutes and with fares starting at just $37, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Charleston, WV, US to Wytheville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charleston to Wytheville?
The cheapest bus tickets from Charleston to Wytheville start from $37. The average price for this route is around $37. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Wytheville?
The average bus trip duration from Charleston to Wytheville is 3h 25m, covering a distance of 106 miles (170 km). The quickest bus can get you there in 3h 25m and is operated by Greyhound.
Which bus companies service the Charleston to Wytheville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Charleston to Wytheville?
The earliest bus departs from Charleston to Wytheville at 5:20am. And the latest bus departs at 5:20am.
What are the CO₂ emissions for the bus trip from Charleston to Wytheville?
A bus trip from Charleston to Wytheville generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, WV, US to Wytheville was searched and found on Nov 29, 2025 with a price of $40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to Wytheville, as early as possible.
You can expect to pay from $40 to $40 for a bus ticket from Charleston, WV, US to Wytheville based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2025-11-29.
Top traveled bus routes
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