How much is the bus ticket from Charleston to Buffalo?

The cheapest bus tickets from Charleston to Buffalo start from $125. The average price for this route is around $150. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Charleston to Buffalo?

The average bus trip duration from Charleston to Buffalo is 1d 6h, covering a distance of 697 miles (1124 km). The quickest bus can get you there in 1d 6h and is operated by Greyhound .

Which bus companies service the Charleston to Buffalo route?

Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Charleston to Buffalo?

The earliest bus departs from Charleston to Buffalo at 11:15am. And the latest bus departs at 11:15am.

What are the CO₂ emissions for the bus trip from Charleston to Buffalo?

A bus trip from Charleston to Buffalo generates an estimated 28 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Charleston to Buffalo?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Charleston to Buffalo?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Charleston to Buffalo?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Charleston to Buffalo?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Charleston to Buffalo from $128 | Refundable Tickets

Previously seen trips

Next departures for Charleston to Buffalo on December 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	1:55pm	4565 Gaynor Ave, North Charleston	1d 3h	5:30pm	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound	Bus	3:15pm	4565 Gaynor Ave, North Charleston	1d 9h	12:45am	Niagara Frontier Transportation Authority	No tags
FlixBus + Greyhound	Bus	3:15pm	4565 Gaynor Ave, North Charleston	1d 9h	12:25am	Buffalo (BUF) Airport	No tags
Greyhound + FlixBus	Bus	1:55pm	4565 Gaynor Ave, North Charleston	1d 8h	10:25pm	Buffalo (BUF) Airport	No tags
	Bus	1:55pm	4565 Gaynor Ave, North Charleston	1d 3h	5:25pm	Niagara Frontier Transportation Authority	No tags

Compare 2 ways to go from Charleston to Buffalo

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 1 day, 8 minutes and with fares starting at just $222, it presents an excellent value for a comfortable ride.

2train per day

1d Average Duration

696 milesDistance

102kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$125 - $512	Average Duration1d 6h	CO₂ emissions 28kg CO₂e
Train	Average Price$222 - $1,857	Average Duration1d	CO₂ emissions 102kg CO₂e

Where are the popular stops in Charleston and Buffalo?

Stops in Charleston

A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405

Stops in Buffalo

A
Buffalo Airport
Visit page
B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Compare bus companies

Greyhound

3.5/587,461 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,801 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Charleston, SC, US to Buffalo, NY by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Charleston to Buffalo?
The cheapest bus tickets from Charleston to Buffalo start from $125. The average price for this route is around $150. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Buffalo?
The average bus trip duration from Charleston to Buffalo is 1d 6h, covering a distance of 697 miles (1124 km). The quickest bus can get you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Charleston to Buffalo route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Charleston to Buffalo?
The earliest bus departs from Charleston to Buffalo at 11:15am. And the latest bus departs at 11:15am.
What are the CO₂ emissions for the bus trip from Charleston to Buffalo?
A bus trip from Charleston to Buffalo generates an estimated 28 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Charleston to Buffalo?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Charleston to Buffalo?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Charleston to Buffalo?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Buffalo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/27

No data

12/28

No data

Today

$192

12/30

No data

12/31

No data

The cheapest trip from Charleston, SC, US to Buffalo, NY was searched and found on Dec 29, 2025 with a price of $192

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Buffalo, NY, as early as possible.