Next departures for Brussels to Frankfurt am Main on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
Cheapest
Bus
Brussels-South (Gare du Midi)
Frankfurt Main Airport P36
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels North Train Station
Frankfurt Hbf
No tags
Next departures for Brussels to Frankfurt am Main on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
Cheapest
Bus
Brussels North Train Station
Frankfurt Hbf
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels-South (Gare du Midi)
Frankfurt Main Airport P36
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Next departures for Brussels to Frankfurt am Main on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
Cheapest
Bus
Brussels North Train Station
Frankfurt Hbf
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels-South (Gare du Midi)
Frankfurt Main Airport P36
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Next departures for Brussels to Frankfurt am Main on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
Frankfurt Hbf
Cheapest
Bus
Brussels North Train Station
Frankfurt Hbf
Fastest
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Next departures for Brussels to Frankfurt am Main on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Bus Station Zone C
Hbf
CheapestFastest
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels-South (Gare du Midi)
Frankfurt Main Airport P36
No tags
Next departures for Brussels to Frankfurt am Main on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
Frankfurt Hbf
Cheapest
Bus
Brussels North Train Station
Frankfurt Hbf
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Next departures for Brussels to Frankfurt am Main on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Frankfurt Hbf
Cheapest
Bus
Brussels North Train Station
Frankfurt Hbf
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels North Train Station
Frankfurt Hbf
No tags
Bus
Brussels South (Gare du Midi)
Frankfurt Hbf
No tags
Next departures for Brussels to Frankfurt am Main on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Frankfurt - Main bus station
Cheapest
Bus
Brussels-South (Gare du Midi)
Frankfurt Main Airport P36
Fastest
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Bus
Brussels Airport
FRA Frankfurt airport
No tags
Last refresh of the prices: Today at 9:32 AM CET.
Compare 3 ways to go from Brussels to Frankfurt am Main
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Frankfurt am Main. The journey takes about 4 hours 10 minutes and with fares starting at just $23, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11143 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $22
BlaBlaBus Brussels Frankfurt am Main recent customer reviews
Everything ran efficiently and was easy for me to understand despite not speaking the native language.
Based on 1946 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the departure location but often complained with the wifi. Union Ivkoni ticket prices on this trip start at $19
Union Ivkoni Brussels Frankfurt am Main recent customer reviews
Arrived 30 minutes late, pick up location is unclear.
Based on 1946 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the departure location but often complained with the wifi. Union Ivkoni ticket prices on this trip start at $19
Union Ivkoni Brussels Frankfurt am Main recent customer reviews
Arrived 30 minutes late, pick up location is unclear.
Musil Tour offers 1 daily departures, and you can find tickets starting at $52. The quickest ride takes around 480. Musil Tour offers a cost-effective solution to get you where you need to be.
Am Hauptbahnhof 8, 60329 Frankfurt am Main, Germany
C - Südbahnhof
Hedderichstraße 51, 60594 Frankfurt am Main, GermanySüdbahnhof
D - Frankfurt Onibus
Stephanstraße 10, 60547 Frankfurt am Main, Germany
E - Braubachstraße 41
Braubachstraße 41, 60311 Frankfurt am Main, Germany
F - Flughafen Hahn Airport (HHN)
Flugplatz Hahn 850, 55483 Lautzenhausen, Germany
Frequently asked questions about traveling from Brussels to Frankfurt am Main by bus
What is the distance between Brussels and Frankfurt am Main?
About 197 miles (318 km) separate Brussels and Frankfurt am Main.
What are the departure and arrival stations when taking the bus from Brussels to Frankfurt am Main?
If you're headed to Frankfurt am Main from Brussels, chances are that your bus will leave from Brussels South (Gare du Midi) and arrive at Frankfurt Airport. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$38
11/19
$38
Today
$24
11/21
$24
11/22
$24
11/23
$29
11/24
$17
11/25
$19
The cheapest trip from Brussels to Frankfurt am Main was searched and found on Nov 24, 2025 with a price of $17
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Frankfurt am Main, as early as possible.
You can expect to pay from $17 to $94 for a bus ticket from Brussels to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2025-11-24.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Brussels to Frankfurt am Main?
The bus is the cheapest travel choice for this destination
The cheapest trip from Brussels to Frankfurt am Main was searched and found on Nov 24, 2025 with a price of $17
The bus is the cheapest travel choice for this destination
