Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | BP Station I-85 & SC-81 | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | BP Station I-85 & SC-81 | Downtown Greyhound Station | Fastest | ||||
| Bus | BP Station I-85 & SC-81 | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | BP Station I-85 & SC-81 | Downtown Greyhound Station | No tags | ||||
| Bus | BP Station I-85 & SC-81 | Downtown Greyhound Station | No tags |
Last refresh of the prices: Last Monday at 5:18 PM EST.
Get from Anderson to Chicago
The journey takes about 23 hours and with fares starting at just $130, it presents an excellent value for a comfortable ride.
Where are the popular stops in Anderson and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Anderson, SC to Chicago by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Anderson, SC to Chicago was searched and found on Nov 30, 2025 with a price of $137To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Anderson, SC to Chicago, as early as possible.
You can expect to pay from $137 to $290 for a bus ticket from Anderson, SC to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $137 which is on 2025-11-30.
