Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Harrisburg Bus Station | Cheapest | ||||
 | Bus | Syracuse (Regional Transportation Center) | Harrisburg Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Harrisburg Bus Station | No tags | ||||
| Bus | Syracuse (Regional Transportation Center) | Harrisburg Bus Station | No tags | ||||
| Bus | Syracuse (Regional Transportation Center) | Harrisburg Bus Station | No tags |
Last refresh of the prices: Yesterday at 1:24 PM EST.
Compare 2 ways to travel from Syracuse to Harrisburg
Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 11 hours 55 minutes and with fares starting at just R 1 250, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Harrisburg?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Compare bus companies
Frequently asked questions about travelling from Syracuse, US to Harrisburg by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Syracuse to Harrisburg?
The cheapest bus tickets from Syracuse to Harrisburg start at R 1 250. The average price for this route is around R 2 181. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Syracuse to Harrisburg?
The average bus journey time from Syracuse to Harrisburg is 11h 55m, covering a distance of 319 km. The fastest bus gets you there in 9h 50m and is operated by Greyhound.
Which bus companies service the Syracuse to Harrisburg route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, FlixBus, New York Trailways, Adirondack Trailways.
What is the earliest and latest departure time for the bus from Syracuse to Harrisburg?
The earliest bus departs from Syracuse to Harrisburg at 00:20. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Syracuse to Harrisburg?
A bus trip from Syracuse to Harrisburg produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Syracuse to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1131 reviews.
Which bus company has the best Wi-Fi from Syracuse to Harrisburg?
Based on reviews on Busbud, the bus company New York Trailways has the best Wi-Fi rating with a score of 3.1.
Which bus company offers the most punctual service from Syracuse to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.8 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Harrisburg was searched and found on 25 Dec 2025 with a price of R 1 965To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Harrisburg as early as possible.
You can expect to pay from R 1 965 to R 3 707 for a bus ticket from Syracuse, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 965, which is on 2025-12-25.
What's the cheapest way to go from Syracuse, US to Harrisburg?
The bus is the cheapest travel choice for this destination
