Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Perugia-Autostazione Piazza Partigiani | Isernia | Cheapest | ||||
| Bus | Perugia (Stazione FS - Fontivegge) | Isernia | Fastest | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia (Stazione FS - Fontivegge) | Isernia | No tags |
Last refresh of the prices: Yesterday at 8:27 AM CET.
Get from Perugia to Isernia
The journey takes about 9 hours 59 minutes, and with fares starting at just R 1 042, it presents an excellent value for a comfortable ride.
Where are the popular stops in Perugia and Isernia?
Stops in Perugia
- AViale Giovanni Perari, 06121 Perugia, Italy
- B
Perugia (P. Partigiani) fermata dell'autobus
Piazza Partigiani, 18, 06121 Perugia, Italy - C
Perugia Stazione
Str. di Prepo, 2, 06129 Perugia, Italy
Compare bus companies
Based on 11631 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 042
Frequently asked questions about travelling from Perugia to Isernia by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Perugia to Isernia?
The cheapest bus tickets from Perugia to Isernia start at R 1 042. The average price for this route is around R 1 042. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Perugia to Isernia?
The average bus journey time from Perugia to Isernia is 9h 59m, covering a distance of 227 km. The fastest bus gets you there in 9h 49m and is operated by FlixBus.
Which bus companies service the Perugia to Isernia route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Perugia to Isernia?
The earliest bus departs from Perugia to Isernia at 01:25. And the latest bus departs at 03:40.
What are the CO₂ emissions for the bus trip from Perugia to Isernia?
A bus trip from Perugia to Isernia produces an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Perugia to Isernia was searched and found on 20 Dec 2025 with a price of R 1 179To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Perugia to Isernia as early as possible.
You can expect to pay from R 1 179 to R 1 499 for a bus ticket from Perugia to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 179, which is on 2025-12-20.
