Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Bus Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Bus Station | Downtown Greyhound Station | Fastest | ||||
| Bus | Bus Station | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Last Tuesday at 11:48 PM EST.
Get from Myrtle Beach to Chicago
The journey takes about 1 day, 3 hours, and with fares starting at just R 2 145, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 87445 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 565
Frequently asked questions about travelling from Myrtle Beach to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Myrtle Beach to Chicago?
The cheapest bus tickets from Myrtle Beach to Chicago start at R 2 145. The average price for this route is around R 2 917. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Myrtle Beach to Chicago?
The average bus journey time from Myrtle Beach to Chicago is 1d 3h, covering a distance of 1191 km. The fastest bus gets you there in 1d 2h and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Chicago route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Chicago?
The earliest bus departs from Myrtle Beach to Chicago at 13:55. And the latest bus departs at 13:55.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Chicago?
A bus trip from Myrtle Beach to Chicago produces an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Chicago was searched and found on 25 Dec 2025 with a price of R 2 760To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Chicago as early as possible.
You can expect to pay from R 2 760 to R 4 576 for a bus ticket from Myrtle Beach to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 760, which is on 2025-12-25.
