Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Key West Bus Station | BILOXI | CheapestFastest | ||||
 | Bus | Key West Bus Station | BILOXI | No tags |
Last refresh of the prices: Today at 11:49 AM EST.
Get from Key West to Biloxi
The journey takes about 1 day, 5 hours 10 minutes, and with fares starting at just R 2 142, it presents an excellent value for a comfortable ride.
Where are the popular stops in Key West and Biloxi?
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Stops in Biloxi
- A11332 Cedar Lake Rd, Biloxi, MS 39532, USA
- B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
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Frequently asked questions about travelling from Key West to Biloxi by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Key West to Biloxi?
The cheapest bus tickets from Key West to Biloxi start at R 2 142. The average price for this route is around R 2 142. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Key West to Biloxi?
The average bus journey time from Key West to Biloxi is 1d 5h, covering a distance of 958 km. The fastest bus gets you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Key West to Biloxi route?
What is the earliest and latest departure time for the bus from Key West to Biloxi?
The earliest bus departs from Key West to Biloxi at 10:00. And the latest bus departs at 17:00.
What are the CO₂ emissions for the bus trip from Key West to Biloxi?
A bus trip from Key West to Biloxi produces an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Key West to Biloxi?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Key West to Biloxi?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Key West to Biloxi?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Key West to Biloxi?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Key West to Biloxi was searched and found on 22 Dec 2025 with a price of R 3 127To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to Biloxi as early as possible.
You can expect to pay from R 3 127 to R 3 127 for a bus ticket from Key West to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 127, which is on 2025-12-22.
