Find coaches from Florence, SC, US to Jacksonville, FL

Next departures

Next departures from Florence to Jacksonville on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Florence, SC
    		Jacksonville Bus StationCheapest
    FlixBus
      		Bus station
      		Jacksonville Bus StationFastest

      Last refresh of the prices: Yesterday at 1:48 AM EDT.

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      Compare 2 ways to travel from Florence to Jacksonville

      We recommend taking the bus

      Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 7 hours 25 minutes and with fares starting at just US$48, it presents an excellent value for a comfortable ride.

      1bus per day
      7h 25mAverage duration
      466 kmDistance
      12kgCO₂ emissions
      Bus
      		Average priceUS$48 - US$89Average duration7h 25m
      12kg CO₂e
      Train
      		Average priceUS$52 - US$145Average duration6h 6m
      42kg CO₂e

      Bus Florence, SC, US to Jacksonville, FL: Trip Overview

      Average ticket priceUS$64
      Average bus trip duration7h 25m
      Number of daily buses1
      Earliest bus departure05:45
      Distance466 km
      Latest bus departure16:00

      Florence to Jacksonville Bus

      Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Jacksonville.

      We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Jacksonville.

      Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Florence, we help you find what you're looking for based on how much of a budget you have.

      Frequently asked questions on the trip Florence, SC, US - Jacksonville, FL

      1. How much does a bus ticket from Florence to Jacksonville cost?

        The bus ticket price from Florence to Jacksonville starts at US$48. The best way to find cheap bus tickets from Florence to Jacksonville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from Florence to Jacksonville?

        The average travel time between Florence and Jacksonville is around 7h 25m, although the fastest bus will take about 5h 25m. This is the time it takes to travel the 472 km that separates the two cities.

      3. How many daily bus connections are there between Florence and Jacksonville?

        The number of buses from Florence to Jacksonville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Jacksonville by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from Florence to Jacksonville?

        When taking the bus from Florence to Jacksonville, you can travel comfortably and safely with FlixBus, Greyhound.

      5. What are the departure and arrival stations when taking the bus from Florence to Jacksonville?

        Buses travelling between Florence and Jacksonville leave from Florence Bus Station or TA Travel Center - Florence and arrive at Jacksonville Amtrak Station, W Forsyth St, Kings Avenue Station.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      31/10
      US$51
      01/11
      US$54
      Today
      US$53
      03/11
      US$45
      04/11
      US$45
      05/11
      US$45
      06/11
      US$43
      07/11
      No data
      busbud logoThe cheapest trip from Florence, SC, US to Jacksonville, FL was searched and found on 06 Nov 2025 with a price of US$43

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Jacksonville, FL as early as possible.

      You can expect to pay from US$43 to US$71 for a bus ticket from Florence, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at US$43, which is on 2025-11-06.

      About Bus Travel

      Bus Travel Tips

      If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Jacksonville but it'll also be endearing to native speakers who will surely appreciate your effort.

      From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Jacksonville.

      Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Jacksonville.

      Make a music playlist for your bus ride from Florence to Jacksonville, and enjoy the scenery to tunes from your own personal soundtrack.

      Did you know?

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

      The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

      What's the cheapest way to go from Florence, SC, US to Jacksonville, FL?

      busbud logoThe bus is the cheapest travel choice for this destination

      Will you be returning to Florence, SC, US by bus?

      Bus from Jacksonville, FL to Florence, SC, US

      You can also go to Jacksonville, FL by train

      Train from Florence, SC, US to Jacksonville, FL

      Why choose Busbud?

      The Best Way To Book Bus and Train Tickets

      Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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