Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | ZOB am Hbf | PRG Airport | Cheapest | |||||
Flixtrain + Flixbus | Hbf | Prague (Main Station - parking) | Fastest | |||||
 | Hbf | Florenc | No tags | |||||
Flixtrain + Flixbus | Hbf | PRG Airport | No tags | |||||
| ZOB am Hbf | PRG Airport | No tags |
Last refresh of the prices: Today at 12:29 AM CET.
Compare 3 ways to travel from Düsseldorf to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 7 hours 20 minutes and with fares starting at just R 759, it presents an excellent value for a comfortable ride.
Where are the popular stops in Düsseldorf and Prague?
Stops in Düsseldorf
- AFernbusbahnhof/Hbf Worringer Str. 140, 40210 Düsseldorf, Germany
- BKonrad-Adenauer-Platz 14, 40210 Düsseldorf, Germany
- C
Bastionstraße, 24
Bastionstraße 24, 40213 Düsseldorf, Germany - D
Kurfürstenstraße
Kurfürstenstraße, 40210 Düsseldorf, Germany - E
Kasernenstraße
Kasernenstraße 3, 40213 Düsseldorf, Germany
Stops in Prague
- AKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- BChlumecká, 198 00 Praha 20, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Frequently asked questions about travelling from Düsseldorf to Prague by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Düsseldorf to Prague?
The cheapest bus tickets from Düsseldorf to Prague start at R 654. The average price for this route is around R 1 355. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Düsseldorf to Prague?
The average bus journey time from Düsseldorf to Prague is 14h, covering a distance of 541 km. The fastest bus gets you there in 9h 58m and is operated by RegioJet.
Which bus companies service the Düsseldorf to Prague route?
Several major bus companies operate on this route with 35 buses available per day, including services from FlixBus, RegioJet, Musil Tour, BlaBlaCar Bus, Infobus.
What is the earliest and latest departure time for the bus from Düsseldorf to Prague?
The earliest bus departs from Düsseldorf to Prague at 01:25. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Düsseldorf to Prague?
A bus trip from Düsseldorf to Prague produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Düsseldorf to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Düsseldorf to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Düsseldorf to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is Infobus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Düsseldorf to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Infobus, with a cleanliness rating of 4.8 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Düsseldorf to Prague was searched and found on 27 Dec 2025 with a price of R 617To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Düsseldorf to Prague as early as possible.
You can expect to pay from R 617 to R 2 574 for a bus ticket from Düsseldorf to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 416, which is on 2025-12-30.
