Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | 4565 Gaynor Ave, North Charleston | Downtown Transit Center | Cheapest | ||||
 | Bus | 4565 Gaynor Ave, North Charleston | Indianapolis Bus Station | Fastest |
Last refresh of the prices: Yesterday at 11:55 AM EST.
Compare 2 ways to travel from Charleston to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 50 minutes and with fares starting at just R 2 305, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and Indianapolis?
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Compare bus companies
Frequently asked questions about travelling from Charleston, SC, US to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Charleston to Indianapolis?
The cheapest bus tickets from Charleston to Indianapolis start at R 2 305. The average price for this route is around R 3 121. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Charleston to Indianapolis?
The average bus journey time from Charleston to Indianapolis is 1d , covering a distance of 944 km. The fastest bus gets you there in 1d and is operated by Greyhound.
Which bus companies service the Charleston to Indianapolis route?
What is the earliest and latest departure time for the bus from Charleston to Indianapolis?
The earliest bus departs from Charleston to Indianapolis at 11:15. And the latest bus departs at 11:15.
What are the CO₂ emissions for the bus trip from Charleston to Indianapolis?
A bus trip from Charleston to Indianapolis produces an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Charleston to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Charleston to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Charleston to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, SC, US to Indianapolis was searched and found on 25 Dec 2025 with a price of R 2 698To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Indianapolis as early as possible.
You can expect to pay from R 2 698 to R 5 327 for a bus ticket from Charleston, SC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 698, which is on 2025-12-25.
What's the cheapest way to go from Charleston, SC, US to Indianapolis?
The bus is the cheapest travel choice for this destination
