Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Buffalo (BUF) Airport | Florence, SC | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags | ||||
FlixBus + Greyhound | Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags | ||||
Greyhound + FlixBus | Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags | ||||
FlixBus + Greyhound | Bus | Buffalo (BUF) Airport | Bus station | No tags |
Compare 2 ways to travel from Buffalo to Florence
Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 22 hours 25 minutes and with fares starting at just R 5 229, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Florence?
Stops in Buffalo
- A
Buffalo Airport
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Florence, SC, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Buffalo to Florence?
The cheapest bus tickets from Buffalo to Florence start at R 5 531. The average price for this route is around R 6 113. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Buffalo to Florence?
The average bus journey time from Buffalo to Florence is 1d 6h, covering a distance of 970 km. The fastest bus gets you there in 1d 4h and is operated by Greyhound.
Which bus companies service the Buffalo to Florence route?
What is the earliest and latest departure time for the bus from Buffalo to Florence?
The earliest bus departs from Buffalo to Florence at 00:55. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Buffalo to Florence?
A bus trip from Buffalo to Florence produces an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Buffalo to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Buffalo to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Buffalo to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Florence, SC, US was searched and found on 20 Dec 2025 with a price of R 6 145To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Florence, SC, US as early as possible.
