Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brussels-North (Gare du Nord) | Mainz | No tags | ||||
| Bus | Brussels Airport | Mainz | No tags | ||||
| Bus | Brussels-North (Gare du Nord) | Mainz | No tags | ||||
| Bus | Brussels Airport | Mainz | No tags | ||||
| Bus | Brussels-North (Gare du Nord) | Mainz | No tags |
Compare 3 ways to travel from Brussels to Mainz
Among the sustainable travel choices, the carpool stands out as a good way to reach Mainz. The journey takes about 3 hours 40 minutes and with fares starting at just R 588, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 11371 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 483
Where are the popular stops in Brussels and Mainz?
Frequently asked questions about travelling from Brussels to Mainz by bus
How much does a bus ticket from Brussels to Mainz cost?
The bus ticket price from Brussels to Mainz starts at R 483. The best way to find cheap bus tickets from Brussels to Mainz is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Brussels to Mainz?
The average travel time between Brussels and Mainz is around 10h 50m, although the fastest bus will take about 5h 25m. This is the time it takes to travel the 295 km that separates the two cities.
How many daily bus connections are there between Brussels and Mainz?
The number of buses from Brussels to Mainz can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brussels to Mainz by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Brussels to Mainz?
When taking the bus from Brussels to Mainz, you can travel comfortably and safely with FlixBus.
What are the departure and arrival stations when taking the bus from Brussels to Mainz?
Buses travelling between Brussels and Mainz leave from Brussels South (Gare du Midi) or Brux-Nord and arrive at Mainz, Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite, Bahnhofstraße.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Mainz was searched and found on 19 Nov 2025 with a price of R 417To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Mainz as early as possible.
You can expect to pay from R 417 to R 1 220 for a bus ticket from Brussels to Mainz based on the last 2 days. You can expect to find the cheapest price for the trip at R 677, which is on 2025-11-24.
