Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Brussels North Train Station | Südseite Hauptbahnhof | CheapestFastest | |||||
| Brussels Airport | Südseite Hauptbahnhof | No tags | |||||
| Brussels Airport | Südseite Hauptbahnhof | No tags | |||||
| Brussels Airport | Südseite Hauptbahnhof | No tags | |||||
| Brussels North Train Station | Südseite Hauptbahnhof | No tags |
Last refresh of the prices: Last Saturday at 3:37 PM CET.
Compare 3 ways to travel from Brussels to Karlsruhe
Among the sustainable travel choices, the carpool stands out as a good way to reach Karlsruhe. The journey takes about 4 hours 50 minutes and with fares starting at just R 860, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Brussels and Karlsruhe?
Frequently asked questions about travelling from Brussels to Karlsruhe by bus
How much does a bus ticket from Brussels to Karlsruhe cost?
The bus ticket price from Brussels to Karlsruhe starts at R 440. The best way to find cheap bus tickets from Brussels to Karlsruhe is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Brussels to Karlsruhe?
The average travel time between Brussels and Karlsruhe is around 10h 45m, although the fastest bus will take about 7h 15m. This is the time it takes to travel the 355 km that separates the two cities.
How many daily bus connections are there between Brussels and Karlsruhe?
The number of buses from Brussels to Karlsruhe can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brussels to Karlsruhe by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Brussels to Karlsruhe?
When taking the bus from Brussels to Karlsruhe, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Brussels to Karlsruhe?
Buses travelling between Brussels and Karlsruhe leave from Brussels South (Gare du Midi) or Brux-Nord and arrive at Südseite Hauptbahnhof, Karlsruhe Hbf, Goethestraße.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Karlsruhe was searched and found on 19 Nov 2025 with a price of R 524To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Karlsruhe as early as possible.
You can expect to pay from R 524 to R 734 for a bus ticket from Brussels to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at R 533, which is on 2025-11-23.
What's the cheapest way to go from Brussels to Karlsruhe?
The bus is the cheapest travel choice for this destination
