Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | CheapestFastest | ||||
Flixbus Chile + Andimar | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags | ||||
Flixbus Chile + Andimar | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags |
Last refresh of the prices: Last Tuesday at 01:17 -03.
Get from Talca to La Serena
The journey takes about 11 hours, and with fares starting at just €20, it presents an excellent value for a comfortable ride.
Where are the popular stops in Talca and La Serena?
Stops in Talca
- ADos Sur / Doce y Trece Oriente, Talca, VII Región, Chile
- B
Parada de Autobus Talca Varoli
Rho 1131, Talca, VII Región, Chile - C
Parada de Autobus Talca Cruce Varoli
Veintiuno Ote 253, Talca, VII Región, Chile - D
Estación de Ferrocarriles de Talca
Once Ote 900-1002, Talca, VII Región, Chile - E
Terminal Tur Bus de Talca
Trece Ote 851-889, Talca, VII Región, Chile - F
Cruce Sur San Javier
Sgto Aldea 2456, San Javier, VII Región, Chile
Stops in La Serena
- AAmunátegui 107, La Serena, Región de Coquimbo, Chile
- B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Compare bus companies
Based on 12136 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at €20
Frequently asked questions about travelling by bus from Talca to La Serena, CL
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Talca to La Serena?
The cheapest coach tickets from Talca to La Serena start from €20. The average price for this route is around €29. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Talca to La Serena?
The average bus journey time from Talca to La Serena is 11h, covering a distance of 617 km. The fastest bus can take you there in 10h 35m and is operated by FlixBus.
Which bus companies service the Talca to La Serena route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Talca to La Serena?
The earliest bus departs from Talca to La Serena at 06:45. And the latest bus departs at 17:45.
What are the CO₂ emissions for the bus trip from Talca to La Serena?
A bus journey from Talca to La Serena produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Talca to La Serena, CL was searched and found on 24 Jan 2026 with a price of €20To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Talca to La Serena, CL as early as possible.
You can expect to pay from €20 to €24 for a bus ticket from Talca to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at €20, which is on 2026-01-24.